18192-31-9

Upstream product

• 769-00-6 (iodomethyl)dimethylphenylsilane 
• 141-97-9 ethyl acetoacetate 
• 100-58-3 phenylmagnesium bromide 
• 105623-17-4 N-(2-methylpropylidene)benzylamine-N-oxide 
• 223245-66-7 ethyl (E)-3-dimethylphenylsilyl-2-propenoate 
• 1141494-33-8 ethyl (2Z)-3-[dimethyl(phenyl)silyl]-2-propenoate 
• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 766-77-8 Dimethylphenylsilane 
• 140-88-5 ethyl acrylate 

Downstream Products

• 18410-34-9 3-(dimethylphenylsilyl)-1,1-dimethyl-1-propanol 
• 17872-96-7 3-[(dimethyl)phenylsilyl]propionic acid 
• 226572-42-5 ethyl 3-(dimethylphenylsilyl)-2,2-dimethylpropionate 
• 261381-46-8 3-(dimethylphenylsilyl)-1-[1,1-2H₂]propanol 
• 17983-34-5 3-(dimethyl(phenyl)silyl)propionyl chloride 
• 120196-08-9 4-dimethyl(phenyl)silylbutan-2-ol 
• 18042-35-8 4-(dimethyl-phenyl-silanyl)-butan-2-one 
• 261381-49-1 3-(dimethylphenylsilyl)[1,1-2H₂]propyl tosylate 

Relevant academic research and scientific papers

A Highly Chemoselective Cobalt Catalyst for the Hydrosilylation of Alkenes using Tertiary Silanes and Hydrosiloxanes

The hydrosilylation of alkene substrates bearing additional functionalities is difficult to achieve using earth-abundant catalysts and has not been extensively realized with both earth-abundant transition metals and tertiary silanes or hydrosiloxanes. Reported herein is a well-defined bis(carbene) cobalt(I)-dinitrogen complex for the efficient, catalytic anti-Markovnikov hydrosilylation of terminal alkenes, featuring a broad substrate scope. Alkenes containing hydroxyl, amino, ester, epoxide, ketone, formyl, and nitrile groups are selectively hydrosilylated in this reaction sequence. Multinuclear NMR studies of reactive intermediates gave insights into the mechanism.

SmI2-mediated cross-coupling of nitrones with β-silyl acrylates: Synthesis of (+)-Australine

The SmI2-mediated cross-coupling of nitrones with β-silyl-α,β-unsaturated esters, followed by zinc reduction, allows an efficient and highly diastereoselective preparation of β-silyl lactams, which are precursors of β-hydroxy lactams through Ta

The γ-silicon effect. I. Solvent effects on the solvolyses of 2,2- dimethyl-3-(trimethylsilyl)propyl and 3-(aryldimethylsilyl)-2,2- dimethylpropyl p-toluenesulfonates

The solvolysis rates of 2,2-dimethyl-3-(trimethylsilyl)propyl and 3- (aryldimethylsilyl)-2,2-dimethylpropyl p-toluenesulfonates were measured in a wide variety of solvents at 45 °C. The solvent effects were analyzed by using the Winstein-Grunwald equation. The solvent effects observed did not give simple linear correlations with the 2-adamantyl Y(OTs) parameter, but showed dispersion behavior in a series of binary solvents. The m values of 0.59-.67 were remarkably lower than unity for the limiting k(c) solvolysis of 2-adamantyl p-toluenesulfonate. The deviation patterns could not be interpreted in terms of nucleophilic assistance by the solvent. The dispersion behavior with reduced m values was found to be more significant for the 3-(aryldimethylsilyl) than for the 3-(trimethylsilyl) derivatives and was compatible with the delocalization of the incipient cationic charge by participation of the Si-Cγ bond in the rate-determining step. An extended dual-parameter treatment, log (k/k(80E)) = m(c)Y(OTs) + m(Δ)Y(Δ), successfully correlated such γ-silyl assisted solvolyses. The M(Δ) values of 0.24-0.49 so obtained, where M(Δ) = 0.51 m(Δ)/(m(c) +0.51 m(Δ)), are a measure of the extent of charge delocalization, suggesting that the γ-silyl group in the percaudal interaction is more effective in delocalizing the cationic charge than the alkyl group in C-C σ-participation, but less so than σ-assisted interaction by the β-aryl group.