72712-21-1

Basic information

• Product Name: ACETIC ACID 2-ACETOXY-5-ACETYL-PHENYL ESTER
• Synonyms: 4-Acetyl-1,2-phenylene diacetate; Acetic acid 2-acetoxy-5-acetyl-phenyl ester; Acetic acid, 2-acetoxy-5-acetylphenyl ester; ethanone, 1-[3,4-bis(acetyloxy)phenyl]-
• CAS NO: 72712-21-1
• Molecular Formula: C₁₂H₁₂O₅
• Molecular Weight: 236.22
• Mol File: 72712-21-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 379.2 °C at 760 mmHg
• Flash Point: 169.5 °C
• Appearance: /
• Density: 1.203 g/cm³
• Vapor Pressure: 5.95E-06mmHg at 25°C
• Refractive Index: 1.512
• CAS DataBase Reference: ACETIC ACID 2-ACETOXY-5-ACETYL-PHENYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: ACETIC ACID 2-ACETOXY-5-ACETYL-PHENYL ESTER(72712-21-1)
• EPA Substance Registry System: ACETIC ACID 2-ACETOXY-5-ACETYL-PHENYL ESTER(72712-21-1)

Safety Data

• Hazardous Substances Data: 72712-21-1(Hazardous Substances Data)

Usage

General Description

ACETIC ACID 2-ACETOXY-5-ACETYL-PHENYL ESTER is a chemical compound with the molecular formula C11H12O4. It is an ester formed from acetic acid and 2-acetoxy-5-acetylphenol. ACETIC ACID 2-ACETOXY-5-ACETYL-PHENYL ESTER is commonly used in the pharmaceutical and cosmetic industries as an intermediate in the synthesis of various drugs and perfumes. It is also used as a flavoring agent in the food industry. Additionally, ACETIC ACID 2-ACETOXY-5-ACETYL-PHENYL ESTER has been studied for its potential biological activities, including its anti-inflammatory and antioxidant properties. However, it is important to handle this compound with care, as it can be hazardous if not properly used and stored.

InChI:InChI=1/C12H12O5/c1-7(13)10-4-5-11(16-8(2)14)12(6-10)17-9(3)15/h4-6H,1-3H3

Upstream product

• 14005-14-2 2,2-dimethyl-1,3-benzodioxole 
• 75-36-5 acetyl chloride 
• 1344113-47-8 C₁₆H₂₆O₃Si 
• 56961-48-9 2-chloro-3′,4′-dihydroxyacetophenone 
• 108-24-7 acetic anhydride 
• 1197-09-7 1-(3,4-dihydroxyphenyl)ethan-1-one 
• 182-55-8 spiro[benzo[d][1,3]dioxole-2,1'-cyclohexane] 
• 105732-47-6 2-methyl-2-benzyl-1,3-benzodioxole 
• 183-32-4 spiro[1,3-benzodioxol-2,1'-cyclopentane] 
• 14049-41-3 2-ethyl-2-methyl-benzo[1,3]dioxole 
• 274-09-9 Methylenedioxybenzene 

Downstream Products

• 409109-83-7 N-(3,4-diacetoxy-phenacyl)-phthalimide 
• 138-65-8 Norepinephrine 
• 1154-78-5 3′,4′,5,7-tetrahydroxyflavylium chloride 
• 29477-55-2 3,4-dihydroxyphenylglyoxal 
• 1197-09-7 1-(3,4-dihydroxyphenyl)ethan-1-one 
• 18393-49-2 3',4',7-trihydroxyflavylium chloride 
• 67632-28-4 2-bromo-1-(3,4-diacetoxy-phenyl)-ethanone 

Relevant articles and documents

Synthesis of catechols from phenols via Pd-catalyzed silanol-directed C-H oxygenation

A silanol-directed, Pd-catalyzed C-H oxygenation of phenols into catechols is presented. This method is highly site selective and general, as it allows for oxygenation of not only electron-neutral but also electron-poor phenols. This method operates via a silanol-directed acetoxylation, followed by a subsequent acid-catalyzed cyclization reaction into a cyclic silicon-protected catechol. A routine desilylation of the silacyle with TBAF uncovers the catechol product.

Studies on the Synthesis of Heterocyclic Compounds. XVI. Cleavage of 1,3-Benzodioxoles and -Benzoxathioles by Sodium Iodide-Acyl Chloride

The cleavage reaction of ethereal and thioethereal bonds with sodium iodide and acyl chloride has been studied.In all the 1,3-benzodioxoles and -benzoxathioles studied, the opening of the heterocyclic ring with formation of 1,2-diacetoxybenzene or 2-hydroxythiophenol diacetic acid ester and gem-diiodoalkanes and iodoalkenes has been observed.The structure of newly prepared compounds has been determined by analytical and spectroscopic data or comparison with authentic samples.