182131-71-1Relevant academic research and scientific papers
Mechanistic insights into the palladiumII-catalyzed hydroxyalkoxylation of 2-allylphenols
Thiery, Emilie,Chevrin, Carole,Le Bras, Jean,Harakat, Dominique,Muzart, Jacques
, p. 1859 - 1862 (2007)
The Pd(OCOCF3)2/[(HOCH2CH 2NHCOCH2)2NCH2]2- catalyzed oxidation of o-allylphenol with H2O2 in water/methanol affords a syn and anti mixture of 2-(1,2-dihydroxypropyl)phenol and 2-(2-hydroxy-1-methoxypropyl)phenol. Mechanistic experiments and ESI-MS studies support a pathway wherein isomerization of the C=C bond followed by its epoxidation and oxirane opening led to the products. Recycling of the catalytic system led to gradual lost of activity.
One-pot catalytic synthesis of 2-(1,2-dihydroxypropyl)phenol derivatives from 2-allylphenols in aqueous media
Chevrin, Carole,Le Bras, Jean,Henin, Francoise,Muzart, Jacques
, p. 2615 - 2618 (2005)
Catalytic amounts of the hydrophilic ligand [(HOCH2CH 2NHCOCH2)2NCH2]2 and palladium(II) salts, in the presence of hydrogen peroxide, water and alcohol, allow the direct transformation of 2
