182181-19-7

Basic information

• Product Name: 6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID
• Synonyms: 6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID;TIMTEC-BB SBB010956;6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID, 95+%;6-chloroimidazo[1,2-a]pyridine-2-carboxylic acid(SALTDATA: 0.5HBr 0.5H2O);6-chloroimidazo[1,2-a]pyridine-2-carboxylic acid 0.5HBr 0.5H2O;2-Carboxy-6-chloroimidazo[1,2-a]pyridine;6-ChloroiMdazo(1,2-A)Pyridine-2-carboxylic acid;6-chloro-2-imidazo[1,2-a]pyridinecarboxylic acid
• CAS NO: 182181-19-7
• Molecular Formula: C8H5ClN2O2
• Molecular Weight: 196.59
• Product Categories: API intermediates;Carboxylic Acids;Fused Ring Systems;Heterocycle-Pyridine series
• Mol File: 182181-19-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 228-229°C
• Appearance: /
• Density: 1.58 g/cm³
• Storage Temp.: 2-8°C
• PKA: -4.71±0.41(Predicted)
• CAS DataBase Reference: 6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID(182181-19-7)
• EPA Substance Registry System: 6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID(182181-19-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 182181-19-7(Hazardous Substances Data)

Usage

General Description

6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID is a chemical compound with a molecular formula C8H5ClN2O2. It is a derivative of imidazo[1,2-a]pyridine and carboxylic acid. 6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID is a chlorinated heterocyclic building block used in the synthesis of various pharmaceuticals and agrochemicals. It has potential applications in medicinal chemistry and drug discovery, particularly in the development of new treatments for various diseases. Additionally, it may also be used as a research tool in chemical biology and bioorganic chemistry.

InChI:InChI=1/C8H5ClN2O2/c9-5-1-2-7-10-6(8(12)13)4-11(7)3-5/h1-4H,(H,12,13)/p-1

Upstream product

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Relevant articles and documents

AMINO-DIHYDROTHIAZINE AND AMINO-DIOXIDO DIHYDROTHIAZINE COMPOUNDS AS BETA-SECRETASE ANTAGONISTS AND METHODS OF USE

The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: wherein variables A4, A5, A6, A8, R1, R2, R3, R7 and n of Formula I, independently, are defined herein. The invention also provides pharmaceutical compositions comprising the compounds, and corresponding uses of the compounds and compositions for treatment of disorders and/or conditions related to A-beta plaque formation and deposition, resulting from the biological activity of BACE. Such BACE mediated disorders include, for example, Alzheimer's Disease, cognitive deficits, cognitive impairments, schizophrenia and other central nervous system conditions. The invention further provides compounds of Formula II and sub-formula embodiments thereof, intermediates and processes and methods useful for the preparation of compounds of Formulas I-II.

IMIDAZO[1,2-A]PYRIDINES FOR THE TREATMENT OF CNS AND CARDIAC DISEASES

The present invention relates to imidazo[1,2-a]pyridine compounds of formula (1) STR1 which are dopamine D-4 antagonists and useful as anti-psychotic agents.