182187-39-9 Usage
General Description
1-PHENYLSULFONYLINDOLE-5-METHANOL is an organic compound that belongs to the indole class of chemicals. It is a derivative of indole with a phenylsulfonyl group attached to the 1-position and a hydroxyl group attached to the 5-position. This chemical is commonly used in organic synthesis as a building block for the production of pharmaceuticals and other organic compounds. It has also been studied for its potential biological activities, particularly in the area of medicinal chemistry. Its unique structure and functional groups make it a versatile and valuable compound for use in chemical and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 182187-39-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,1,8 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 182187-39:
(8*1)+(7*8)+(6*2)+(5*1)+(4*8)+(3*7)+(2*3)+(1*9)=149
149 % 10 = 9
So 182187-39-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H13NO3S/c17-11-12-6-7-15-13(10-12)8-9-16(15)20(18,19)14-4-2-1-3-5-14/h1-10,17H,11H2
182187-39-9Relevant articles and documents
METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION
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, (2017/09/06)
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer. The present disclosure describes compounds and methods to recover wild-type function to p53 mutants. The compounds of the present invention can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA and activate downstream effectors involved in tumor suppression. The disclosed compounds can be used to reduce the progression of cancers that contain a p53 mutation.