182217-23-8

Basic information

• Product Name: 3-tert-butyl-2-hydroxy-5-triphenylmethylbenzaldehyde
• Synonyms: 3-tert-butyl-2-hydroxy-5-triphenylmethylbenzaldehyde
• CAS NO: 182217-23-8
• Molecular Weight: 420.551
• Mol File: 182217-23-8.mol

Chemical Properties

• CAS DataBase Reference: 3-tert-butyl-2-hydroxy-5-triphenylmethylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-tert-butyl-2-hydroxy-5-triphenylmethylbenzaldehyde(182217-23-8)
• EPA Substance Registry System: 3-tert-butyl-2-hydroxy-5-triphenylmethylbenzaldehyde(182217-23-8)

Safety Data

• Hazardous Substances Data: 182217-23-8(Hazardous Substances Data)

Upstream product

• 88-18-6 2-tert-Butylphenol 
• 100-97-0 hexamethylenetetramine 
• 60043-12-1 2-tert-butyl-4-triphenylmethylphenol 
• 50-00-0 formaldehyd 

Downstream Products

• 1127288-86-1 2-tert-butyl-4-triphenylmethyl-6-[(4-triphenylmethylphenylimino)methyl]phenol 
• 1397334-54-1 2-((E)-(((1R,2R)-2-amino-1,2-diphenylethyl)imino)methyl)-6-(tert-butyl)-4-tritylphenol 

Relevant articles and documents

Carbonylative, Catalytic Deoxygenation of 2,3-Disubstituted Epoxides with Inversion of Stereochemistry: An Alternative Alkene Isomerization Method

Reactions facilitating inversion of alkene stereochemistry are rare, sought-after transformations in the field of modern organic synthesis. Although a number of isomerization reactions exist, most methods require specific, highly activated substrates to achieve appreciable conversion without side product formation. Motivated by stereoinvertive epoxide carbonylation reactions, we developed a two-step epoxidation/deoxygenation process that results in overall inversion of alkene stereochemistry. Unlike most deoxygenation systems, carbon monoxide was used as the terminal reductant, preventing difficult postreaction separations, given the gaseous nature of the resulting carbon dioxide byproduct. Various alkyl-substituted cis- A nd trans-epoxides can be reduced to trans- A nd cis-alkenes, respectively, in >99:1 stereospecificity and up to 95% yield, providing an alternative to traditional, direct isomerization approaches.

Synthesis of salicylaldehydes bearing bulky substituents in the positions 3 and 5

Reaction of 2,4-disubstituted phenols with paraformaldehyde in the presence of SnCl4 and 2,6-lutidine afforded a number of new salicylaldehydes, containing bulky substituents (tert-butyl, 1-phenylethyl, 1-(4-tert- butylphenyl)ethyl, α-cumyl, and trityl) in the positions 3 and 5.

Asymmetric epoxidation of unfunctionalized alkenes with ammonium and phosphonium monopersulfates catalyzed by chiral Mn(III)-salen complexes

Simple cis-disubstituted and trisubstituted alkenes were enantioselectively epoxidized in mild conditions using various Mn(III)-salen complexes as catalysts and quaternary ammonium and phosphonium monopersulfates (Bu4NHSO5, Ph4