182223-53-6 Usage
Description
1-Benzyl-4-benzyloxycarbonylaminopiperidine is an organic compound that serves as an intermediate in the synthesis of various pharmaceuticals. It is characterized by its pale-yellow solid appearance and plays a crucial role in the development of p-38 kinase inhibitors and serotonin antagonists.
Uses
Used in Pharmaceutical Industry:
1-Benzyl-4-benzyloxycarbonylaminopiperidine is used as a chemical intermediate for the preparation of p-38 kinase inhibitors and serotonin antagonists. Its role in the synthesis of these compounds is vital for the development of medications targeting specific biological pathways and receptors, thereby contributing to the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 182223-53-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,2,2 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 182223-53:
(8*1)+(7*8)+(6*2)+(5*2)+(4*2)+(3*3)+(2*5)+(1*3)=116
116 % 10 = 6
So 182223-53-6 is a valid CAS Registry Number.
InChI:InChI=1/C20H24N2O2/c23-20(24-16-18-9-5-2-6-10-18)21-19-11-13-22(14-12-19)15-17-7-3-1-4-8-17/h1-10,19H,11-16H2,(H,21,23)
182223-53-6Relevant articles and documents
Imidazo-substituted compounds as p38 kinase inhibitors
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Page 14, (2008/06/13)
The present invention discloses compounds corresponding to formula I: wherein A, Z, Z1, Y, R1 and R2 are as defined in the specification, as well as pharmaceutical formulations, methods of making and uses thereof.
Synthesis and structure-activity relationships of potent and orally active 5-HT4 receptor antagonists: Indazole and benzimidazolone derivatives
Schaus, John M.,Thompson, Dennis C.,Bloomquist, William E.,Susemichel, Alice D.,Calligaro, David O.,Cohen, Marlene L.
, p. 1943 - 1955 (2007/10/03)
A series of indole-3-carboxamides, indazole-3-carboxamides, and benzimidazolone-3-carboxamides was synthesized and evaluated for antagonist affinity at the 5-HT4 receptor in the rat esophagus. The endo-3-tropanamine derivatives in the indazole