18226-53-4Relevant academic research and scientific papers
Enaminonitriles in heterocyclic synthesis: A route to 1,3-diaryl-4- Aminopyrazole derivatives
Medrasi, Hanadi Y.,Al-Sheikh, Mariam Abdullah,Salaheldin, Abdellatif Mohamed
, p. 535 - 544 (2013/03/13)
Benzylcyanide and 4-nitrobenzylcyanide condensed with triethyl orthoformate and piperidine or morpholine to yield 2-Aryl-2-piperidinyl or 2-morpholinylacrylonitriles. These coupled with aromatic diazonium salts to yield the 2-Arylhydrazno-2-Arylethane nit
Studies with enamines: Route to aminoazolopyrimidines and arylazoazolopyrimidines
Salaheldin, Abdellatif M.,Khairou, Khalid S.
, p. 175 - 181 (2013/04/23)
An easy preparation of enaminonitrile derivatives and their transformation into new substituted azolopyrimidines is described. The one-step transformation was carried out under microwave irradiation and by classical heating methods. The use of microwave i
Enamines in heterocyclic synthesis: A novel simple and efficient route to condensed pyridazines
Darwisha, Elham S.,Abdelrahmana, Mahmoud A.,Salaheldin, Abdellatif M.
supporting information; experimental part, p. 597 - 602 (2011/08/04)
An efficient and easy preparation of enamine derivatives, via active methyl and methylene compounds by in situ-generated 1-(diethoxymethyl)piperidine, produced from the mixture of triethyl orthoformate/piperidine/DMF, are described. Some new pyridazinone
Enaminonitriles in heterocyclic synthesis: Novel synthesis of 3-aminopyrroles and pyrrolo[3,2-d] pyrimidine derivatives
Salaheldin, Abdellatif M.
experimental part, p. 564 - 570 (2009/02/03)
Several new 3-aminopyrrole derivatives have been synthesized from 3-substituted amino-2-phenylacrylonitriles using Thorpe-Ziegler cyclization. These substituted pyrroles are readily converted into 5H-pyrrolo[3,2-d] pyrimidines (9-deazapurines).
