18228-69-8

Basic information

• Product Name: 1-[2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropyl]ethanone
• CAS NO: 18228-69-8
• Molecular Formula: C₁₁H₁₈O
• Molecular Weight: 166.26
• Mol File: 18228-69-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 208.1°C at 760 mmHg
• Flash Point: 73.2°C
• Density: 0.949g/cm³
• Vapor Pressure: 0.217mmHg at 25°C
• Refractive Index: 1.512
• CAS DataBase Reference: 1-[2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropyl]ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropyl]ethanone(18228-69-8)
• EPA Substance Registry System: 1-[2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropyl]ethanone(18228-69-8)

Safety Data

• Hazardous Substances Data: 18228-69-8(Hazardous Substances Data)

Usage

Type of compound

Cyclopropyl ketone

Structural features

Contains a cyclopropane ring
Contains a double bond

Reactivity

Unique reactivity due to its structure

Applications

Used in organic synthesis
Used in pharmaceutical research

Biological and pharmacological activities

Studied for potential activities, making it an important target in medicinal chemistry

Potential use

Serve as a building block in the synthesis of various biologically active molecules with potential therapeutic applications

Upstream product

• 5460-63-9 chrysanthemumic acid methyl ester 
• 75-16-1 methylmagnesium bromide 
• 18228-69-8 cis-chrysanthemyl methyl ketone 
• 2935-23-1 cis-Chrysanthemic acid 
• 917-54-4 methyllithium 
• 97-41-6 ethyl trans-(+/-)-chrysanthemate 
• 827-90-7 trans-chrysanthemic acid 
• 917-64-6 methyl magnesium iodide 
• 51348-74-4 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropane-1-carbonyl chloride 

Downstream Products

• 18228-69-8 rac-trans-1-(-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropyl)ethanone 
• 105140-56-5 2-((E)-1,1,4,4-Tetramethyl-6-oxo-hept-2-enyl)-cyclohexanone 

Relevant articles and documents

Chemoselective reduction of aldehydes: Via a combination of NaBH4 and acetylacetone

A bench-stable combination of NaBH4-acetylacetone was developed for the efficient chemoselective reduction of aldehydes in the presence of ketones. This method offers a useful synthetic protocol for distinguishing carbonyl reaction sites, and its synthetic utility is reflected by its moisture tolerance and high efficiency in a variety of complex settings.

The effects of triplet sensitizers' energies on the photoreactivity of β,γ-unsaturated methyl ketones

(Chemical Equation Presented) Triplet determines reactivity: β,γ-Unsaturated ketones 1 do not undergo the oxa-di-π-methane (ODPM) rearrangement in the presence of acetophenone or 3-methoxyacetophenone as a triplet sensitizer. However, they afford the ODPM