1823-77-4

Upstream product

• 64-18-6 formic acid 
• 141-53-7 sodium formate 
• 3883-94-1 2-amino-4'-methoxyacetophenone hydrochloride 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 129972-93-6 C₁₁H₁₁NO₄ 
• 18197-26-7 sodium diformamide 

Downstream Products

• 1250-16-4 N,N'-Diformyl-1,2-bis-<4-methoxy-benzoyl>-ethylendiamin 
• 1823-80-9 2-Isocyan-1-<4-methoxy-phenyl>-aethanon 
• 1823-84-3 2-(4-Methoxyphenyl)vinyl Isocyanide 
• 1823-82-1 2-Formylamino-1-(4-methoxy-phenyl)-aethanol-⁽¹⁾ 

Relevant academic research and scientific papers

THROMBOPOETIN RECEPTOR ACTIVATOR AND PROCESS FOR PRODUCING THE SAME

A preventive, therapeutic or improving agent for diseases against which activation of the thrombopoietin receptor is effective or a platelet increasing agent, which contains a thrombopoietin receptor activator represented by the formula (1): [wherein each

A Convenient Synthesis of Aminomethyl Ketones (α-Amino Ketones)

Several N,N-diformylaminomethyl ketones 3 were prepared by treating the respective bromomethylketone 1 with sodium diformylamide in acetonitrile at room temperature.This reaction produced from N-formylaminomethyl ketones 4 when ethanol was used as the solvent.One of the formyl groups of N,N-difomylaminomethyl ketones was selectively removed by using a catalytic amount of sodium or potassium hydroxide in alcohol to the corresponding N-formylaminomethyl ketones 4.The formyl groups of both N,N-diformyl- and N-formylaminomethyl ketones could be easily removed by either5percent hydrochloric acid in ethanol or 6N hydrochloric acid to give the corresponding aminomethyl ketone hydrochlorides 5.These reactions are general and give high yield of the products.