182355-74-4

Upstream product

• 2127-03-9 2,2'-dipyridyldisulphide 
• 205593-86-8 3,4,6-tri-O-benzyl-2-deoxy-2-azido-β-D-galactopyranosyl 2,2,2-trichloroacetimidate 
• 182355-71-1 2-pyridyl 2-azido-2-deoxy-3,4,6-tri-O-benzyl-1-thio-α-D-galactopyranoside 
• 2637-34-5 2-Sulfanylpyridine 

Downstream Products

• 182355-75-5 N-[(2R,3R,4R,5R,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-2-(pyridine-2-sulfonyl)-tetrahydro-pyran-3-yl]-acetamide 

Relevant academic research and scientific papers

Stereocontrolled synthesis of α-C-galactosamine derivatives promoted by samarium diiodide: An example of chelation controlled C-glycosylation

Direct coupling of the pyridylsulfone of N-acetylgalactosamine with aldehydes or ketones is promoted by samarium diiodide unexpectedly giving the corresponding α-C-glycosides.

Stereocontrolled Synthesis of α-C-Galactosamine Derivatives via Chelation-Controlled C-Glycosylation

The samarium diiodide-promoted reduction of 2-deoxy-2-acetamidogalactosyl pyridyl sulfone α-5 with ketones or aldehydes under Barbier conditions led unexpectedly to the stereoselective synthesis of α-C-galactosamine derivatives in good yields. With carbon