182748-90-9

Upstream product

• 152500-26-0 (S)-5-(hydroxymethyl)-1-(4-methoxyphenylmethyl)-2-pyrrolidinone 
• 124-63-0 methanesulfonyl chloride 
• 73995-62-7 (S)-2-{[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-amino}-pentanedioic acid dimethyl ester 
• 87341-38-6 methyl (2S)-1-(4-methoxybenzyl)pyroglutamate 
• 123-11-5 4-methoxy-benzaldehyde 
• 6525-53-7 L-glutamic acid dimethyl ester 

Downstream Products

• 182748-92-1 ethyl (S)-(+)-[1-(4-methoxybenzyl)-5-oxo-pyrrolidin-2-yl]acetate 
• 182748-91-0 (S)-(+)-[1-(4-methoxybenzyl)-5-oxo-pyrrolidin-2-yl]acetonitrile 

Relevant academic research and scientific papers

Oxidation of N-(4-methoxybenzyl)-2-pyrrolidinones to N-(4-methoxybenzoyl)-2-pyrrolidinones. Rapid entry to optically active aniracetam analogues

Oxidation of readily available N-(4-methoxybenzyl)-5-alkylpyrrolidin-2-ones to the corresponding N-(4-methoxybenzoyl)-5-alkylpyrrolidin-2-ones gives direct access to enantiomerically pure 5-alkyl analogues of the cognition activating agent Aniracetam.