182949-58-2

Basic information

• Product Name: C₁₃H₁₉NO₂S
• CAS NO: 182949-58-2
• Molecular Weight: 253.365
• Mol File: 182949-58-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₉NO₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₉NO₂S(182949-58-2)
• EPA Substance Registry System: C₁₃H₁₉NO₂S(182949-58-2)

Safety Data

• Hazardous Substances Data: 182949-58-2(Hazardous Substances Data)

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 108-10-1 4-methyl-2-pentanone 

Downstream Products

• 1231765-37-9 (2R,3R)-2-isobutyl-2-methyl-4-methylene-1-tosylpyrrolidine-3-carbonitrile 
• 24118-70-5 (R)-N-1-(i-butyl)ethyltosylamide 

Relevant articles and documents

Asymmetric Stepwise Reductive Amination of Sulfonamides, Sulfamates, and a Phosphinamide by Nickel Catalysis

Asymmetric reductive amination of poorly nucleophilic sulfonamides was realized in the presence of nickel catalysts and titanium alkoxide. A wide range of ketones, including enolizable ketones and some biaryl ones, were converted into sulfonamides in excellent enantiomeric excess. The cyclization of sulfamates and intermolecular reductive amination of a diarylphosphinamide were also successful. Formic acid was used as a safe and economic surrogate of high-pressure hydrogen gas.