183016-40-2

Basic information

• Product Name: [(Benzhydryl-amino)-pyridin-2-yl-methyl]-phosphonic acid diethyl ester
• Synonyms: [(Benzhydryl-amino)-pyridin-2-yl-methyl]-phosphonic acid diethyl ester
• CAS NO: 183016-40-2
• Molecular Weight: 410.453
• Mol File: 183016-40-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [(Benzhydryl-amino)-pyridin-2-yl-methyl]-phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(Benzhydryl-amino)-pyridin-2-yl-methyl]-phosphonic acid diethyl ester(183016-40-2)
• EPA Substance Registry System: [(Benzhydryl-amino)-pyridin-2-yl-methyl]-phosphonic acid diethyl ester(183016-40-2)

Safety Data

• Hazardous Substances Data: 183016-40-2(Hazardous Substances Data)

Upstream product

• 15192-56-0 2-(diphenylmethyliminomethyl)pyridine 
• 762-04-9 phosphonic acid diethyl ester 
• 1121-60-4 pyridine-2-carbaldehyde 
• 91-00-9 Benzhydrylamine 

Downstream Products

• 3731-51-9 2-(Aminomethyl)pyridine 

Relevant articles and documents

The acidic cleavage of pyridylmethyl(amino)phosphonates. Formation of the corresponding amines

Hydrolysis of 3-pyridylmethyl(amino)phosphonates by means of 20% aq. hydrochloric acid gave corresponding 3-pyridimethyl(amino)phosphonic acids, as expected. However, hydrolysis of 2- and 4-pyridylmethyl(amino)phosphonates led to decomposition of the phosphonates with a cleavage of C-P bond and formation of the corresponding amines. The leaving phosphorus moiety was identified as phosphoric acid. The scope of the reaction is limited to 2- and 4-pyridylmethyl derivatives of aminophosphonic acids and their esters, as well as to the derivatives possessing similar structure. On the contrary, the basic hydrolysis of 2- and 4-pyridylmethyl(amino)phosphonates led to the corresponding monoalkyl esters of the aminophosphonates, and no cleavage of C-P bond was observed in those cases.