183279-05-2

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 183279-01-8 4-amino-6,7-dimethyl-1-(2-deoxy-β-D-ribofuranosyl)pteridine-2-one 
• 183279-00-7 C₂₉H₂₈N₄O₆S 
• 50256-07-0 1-[O³,O⁵-bis-(4-methyl-benzoyl)-β-D-erythro-2-deoxy-pentofuranosyl]-6,7-dimethyl-1H-pteridine-2,4-dione 

Downstream Products

• 183279-06-3 N-(1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6,7-dimethyl-2-oxo-1,2-dihydro-pteridin-4-yl)-benzamide 

Relevant academic research and scientific papers

Synthesis of Mixed Oligonucleotides Containing 6,7-Dimethylisopterin as Modified Aglycone

6,7-Dimethyl-1-(2-deoxy-β-D-ribofuranosyl)isopterin 3 was prepared from 6,7-dimethyl-1-(2-deoxy-3,5-di-O-p-toluoyl-β-D-ribofuranosyl)lumazine via thiation and displacement of the thio function with ammonia.It was then converted into the corresponding N4-benzoyl and N4-p-nitrophenylethoxycarbonyl phosphoramidite building blocks.Mixed oligonucleotides containing 6,7-dimethylisopterin as a modified base were synthesised using solid phase phosphoramidite strategy.