183281-88-1Relevant academic research and scientific papers
Studies on synthesis and structure of O-β-D- ribofuranosyl(1'→2')ribonucleosides and oligonucleotides
Markiewicz, Wojciech T.,Niewczyk, Anna,Gdaniec, Zofia,Adamiak, Dorota A.,Dauter, Zbigniew,Rypniewski, Wojciech,Chmielewski, Marcin
, p. 411 - 424 (2007/10/03)
Minor nucleosides found in several eukaryotic initiator tRNAs(i)(Met), O-β-D-ribofuranosyl(1'→2')adenosine and -guanosine (Ar and Gr), as well as their pyrimidine analogues, were obtained from N-protected 3',5'-O-(1,1,3,3- tetraisopropyldisiloxane-1,3-diyl)ribonucleosides and 1-O-acetyl-2,3,5-tri- O-benzoyl-β-D-ribofuranose in the presence of tin tetrachloride in 1,2- dichloroethane. A crystal structure has been solved for 2'-O-ribosyluridine. The 3'-phosphoramidites of protected 2'-O-ribosylribonucleosides were prepared as the reagents for 2'-O-ribofuranosyloligonucleotides synthesis. O- β-D-Ribofuranosyl(1'→2')adenylyl(3'→5')guanosine (ArpG) was obtained and its structure was analyzed by NMR spectroscopy.
An efficient synthesis and physico-chemical properties of 2′-O-D-ribofuranosylnucleosides, minor tRNA components
Mikhailov, Sergey N.,Efimtseva, Ekaterina V.,Gurskaya, Galina V.,Fomitcheva, Marina V.,Meshkov, Sergey V.,Zavodnik, Valery E.,De Bruyn, Andre,Janssen, Gerard,Rozenski, Jef,Herdewijn, Piet
, p. 75 - 92 (2007/10/03)
A high yield preparation of 9-(2-O-β-D-ribofuranosyl-β-D-ribofuranosyl)adenine, guanine- and the pyrimidine analogs (cytosine, thymine and uracil base moiety) has been achieved, and the conformational properties of the ring systems were investigated using NMR spectroscopy and X-ray.
Synthesis and properties of some 2'-O-D-ribofuranosyl-nucleosides
Mikhailov,De Bruyn,Herdewijn
, p. 481 - 484 (2007/10/02)
A high yield preparation of 9-(2-O-β-D-ribofuranosyl-β-D- ribofuranosyl)-adenine and its pyrimidine analogues has been achieved and their physico-chemical properties were investigated.
