1833-40-5

Usage

Uses

Used in Organic Synthesis:
(2-fluorobenzyl)(trimethyl)silane is used as a reagent for the formation of carbon-silicon bonds in organic synthesis. Its unique structure allows it to act as a versatile building block for the synthesis of various organic compounds.
Used as a Protecting Group:
In organic chemistry reactions, (2-fluorobenzyl)(trimethyl)silane is used as a protecting group for alcohols and carboxylic acids. This helps prevent unwanted side reactions and allows for selective reactions to occur.
Used in Pharmaceutical Production:
(2-fluorobenzyl)(trimethyl)silane serves as a precursor in the production of pharmaceuticals. Its unique properties make it a valuable component in the synthesis of various drug molecules.
Used in Agrochemical Production:
This organosilicon compound is also used as a precursor in the production of agrochemicals, contributing to the development of effective and targeted pesticides and other agricultural products.
Used in Materials Science:
(2-fluorobenzyl)(trimethyl)silane finds applications in materials science, where it is utilized in the development of new materials with specific properties, such as improved thermal stability or enhanced chemical resistance.

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 348-52-7 1-Fluoro-2-iodobenzene 
• 69833-15-4 tris{(trimethylsilyl)methyl}indium 

Relevant academic research and scientific papers

Fluoroalkylselenolation of Alkyl Silanes/Trifluoroborates under Metal-Free Visible-Light Photoredox Catalysis

Herein a metal-free fluoroalkylselenolation of alkylsilanes as well as potassium alkyltrifluoroborates under visible light photocatalysis is disclosed. The developed methodologies are performed under mild conditions, room temperature in the presence of an organic photocatalyst and blue LED irradiation. Mechanistic investigations including luminescence and EPR spectroscopy allow us to shed light on both mechanisms.

Synthesis of Polysubstituted Iodoarenes Enabled by Iterative Iodine-Directed para and ortho C?H Functionalization

Among halogenated aromatics, iodoarenes are unique in their ability to produce the bench-stable halogen(III) form. Earlier, such iodine(III) centers were shown to enable C?H functionalization ortho to iodine via halogen-centered rearrangement. The broader implications of this phenomenon are explored by testing the extent of an unusual iodane-directed para C?H benzylation, as well as by developing an efficient C?H coupling with sulfonyl-substituted allylic silanes. Through the combination of the one-shot nature of the coupling event and the iodine retention, multisubstituted arenes can be prepared by sequentially engaging up to three aromatic C?H sites. This type of iodine-based iterative synthesis will serve as a tool for the formation of value-added aromatic cores.