183378-43-0

Basic information

• Product Name: N⁶-[(allyloxy)carbonyl]-2'-O-(tert-butyldimethylsilyl)-5'-O-(p,p'-dimethoxytrityl)adenosine 3'-(allyl N,N'-diisopropylphosphoramidite)
• Synonyms: N⁶-[(allyloxy)carbonyl]-2'-O-(tert-butyldimethylsilyl)-5'-O-(p,p'-dimethoxytrityl)adenosine 3'-(allyl N,N'-diisopropylphosphoramidite)
• CAS NO: 183378-43-0
• Molecular Weight: 955.176
• Mol File: 183378-43-0.mol

Chemical Properties

• CAS DataBase Reference: N⁶-[(allyloxy)carbonyl]-2'-O-(tert-butyldimethylsilyl)-5'-O-(p,p'-dimethoxytrityl)adenosine 3'-(allyl N,N'-diisopropylphosphoramidite)(CAS DataBase Reference)
• NIST Chemistry Reference: N⁶-[(allyloxy)carbonyl]-2'-O-(tert-butyldimethylsilyl)-5'-O-(p,p'-dimethoxytrityl)adenosine 3'-(allyl N,N'-diisopropylphosphoramidite)(183378-43-0)
• EPA Substance Registry System: N⁶-[(allyloxy)carbonyl]-2'-O-(tert-butyldimethylsilyl)-5'-O-(p,p'-dimethoxytrityl)adenosine 3'-(allyl N,N'-diisopropylphosphoramidite)(183378-43-0)

Safety Data

• Hazardous Substances Data: 183378-43-0(Hazardous Substances Data)

Upstream product

• 108554-72-9 (allyloxy)bis(diisopropylamino)phosphine 
• 185628-20-0 N⁶-[(allyloxy)carbonyl]-5'-O-(p,p'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)adenosine 
• 10457-15-5 O^2'_,O3'_,O5'-tris-trimethylsilanyl-adenosine 
• 58-61-7 adenosine 
• 210684-26-7 N⁶-[(allyloxy)carbonyl]-5'-O-(p,p'-dimethoxytrityl)adenosine 
• 210684-23-4 N⁶-[(allyloxy)carbonyl]adenosine 

Relevant articles and documents

Improved methods for the preparation of 2'-deoxyribonucleoside and ribonucleoside 3'-phosphoramidites with allylic protectors

Improved methods of preparing 2'-deoxyribonucleoside and ribonucleoside 3'phosphoramidites with allylic protecting groups, which serve as useful building blocks, particularly for the synthesis of base-labile derivatives, are developed.

A convenient way to N-allyloxycarbonyl protected adenosine and cytidine derivatives

A convenient method for the introduction of an allyloxycarbonyl protector to adenyl and cytosyl bases using commercially available allyloxycarbonyl chloride as the protecting reagent has been developed.