183388-64-9

Basic information

• Product Name: (2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate
• Synonyms: (2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexne 1/2 succinate (BDH Succinate salt);(2S,3S,5S)-2-Amino-3-hydroxy-5-(tert-butyloxy carbonyl)amino-1,6-diphenylhexane succinate;(2S,3S,5S)-2-aMino-3-hydroxy-5-(tert-butyloxycarbonyl)aMino-1,6-diphenyl heMi succinic acid salt (BDH succinic acid salt);(2S,3S,5S)-2-aMino-3-hydroxy-5-(t-butyloxycarbonylaMino)-1,6-diphenylhexane heMi succinic acid salt;(2s,3s,5s)-5-tert-butyloxycarbonylaMino-2-aMino-3-hydroxy-1,6-diphenylhexane succinate(BDH Succinate Salt);BDH SUCCINIC ACID SALT;bdh succinate salt;(2s,3s,5s)-5-tert-butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate
• CAS NO: 183388-64-9
• Molecular Formula: 2C23H32N2O3.C4H6O4
• Molecular Weight: 887.12
• Mol File: 183388-64-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 569.2ºC at 760 mmHg
• Flash Point: 298ºC
• Appearance: /
• Vapor Pressure: 8.56E-14mmHg at 25°C
• CAS DataBase Reference: (2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate(183388-64-9)
• EPA Substance Registry System: (2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate(183388-64-9)

Safety Data

• Hazardous Substances Data: 183388-64-9(Hazardous Substances Data)

Usage

Description

(2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate is a complex chemical compound that features a succinate group attached to a 1,6-diphenylhexane backbone. (2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate is a derivative of the amino acid valine, with a tert-butyloxycarbonylamino group at the 5th carbon, and includes an amino and hydroxy group. Its unique structure and potential biological activity suggest it may have applications in the pharmaceutical industry, particularly in drug development. Further research is required to explore its properties and uses.

Uses

Used in Pharmaceutical Industry:
(2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate is used as a potential candidate for drug development due to its unique molecular structure and the possibility of exhibiting biological activity that could be harnessed for therapeutic purposes.
Further applications may be discovered as research progresses, but currently, the primary focus is on its potential within the pharmaceutical sector for creating new drugs that could address various health conditions. (2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate's specific uses will depend on the results of ongoing studies and its demonstrated efficacy and safety in preclinical and clinical trials.

InChI:InChI=1/C23H32N2O3.C4H6O4/c1-23(2,3)28-22(27)25-19(14-17-10-6-4-7-11-17)16-21(26)20(24)15-18-12-8-5-9-13-18;5-3(6)1-2-4(7)8/h4-13,19-21,26H,14-16,24H2,1-3H3,(H,25,27);1-2H2,(H,5,6)(H,7,8)/t19-,20-,21-;/m0./s1

Upstream product

• 110-15-6 succinic acid 
• 63-91-2 L-phenylalanine 
• 144163-85-9 (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane 

Downstream Products

• 192725-45-4 (2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane 

Relevant articles and documents

Diastereoselective synthesis of a core fragment of ritonavir and lopinavir

A novel approach to the synthesis of Boc-core, a key starting material for ritonavir and lopinavir involving an unprecedented diastereoselective nitroaldol reaction on β-amino aldehyde is disclosed.

HIV protease inhibiting compounds

A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

RETROVIRAL PROTEASE INHIBITING COMPOUNDS

A compound of the formula: STR1 is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.