18356-28-0 Usage
General Description
Rolziracetam is a nootropic drug that belongs to the racetam class of compounds, which are known for their cognitive enhancement and neuroprotective effects. It is considered to be an analog of piracetam, with similar mechanisms of action but stronger potency. Rolziracetam is thought to exert its effects by modulating the activity of neurotransmitters in the brain, particularly acetylcholine and glutamate. It has been studied for its potential use in treating various cognitive disorders, such as Alzheimer's disease and age-related cognitive decline, as well as for its ability to improve memory, learning, and attention. Clinical studies have suggested that this compound may have neuroprotective properties, making it a potential candidate for the treatment of neurodegenerative diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 18356-28-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,5 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 18356-28:
(7*1)+(6*8)+(5*3)+(4*5)+(3*6)+(2*2)+(1*8)=120
120 % 10 = 0
So 18356-28-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H9NO2/c9-6-3-1-5-2-4-7(10)8(5)6/h5H,1-4H2
18356-28-0Relevant articles and documents
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Leonard et al.
, p. 690 (1947)
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IMPROVED SYNTHESIS OF THE LUKES-SORM DILACTAM. NUCLEOPHILIC OPENING TO 5-SUBSTITUTED 2-PYRROLIDINE-2-ONES
Alonso, Ricardo,Gessner, Wieslaw,Takahashi, Kimio,Brossi, Arnold
, p. 37 - 44 (2007/10/02)
An improved synthesis of the Lukes-Sorm dilactam 3 and conversion into several 5-substituted pyrrolidine-2-ones are described.
Process for the preparation of dihydro-1H-pyrrolizine-3,5-(2H,6H)-dione
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, (2008/06/13)
Dihydro-1H-pyrrolizine-3,5-(2H,6H)-dione is produced in higher overall yield in a process which comprises catalytically hydrogenating a lower alkyl ester of 4-(hydroxyimino)heptanedioic acid in the presence of a tri-(lower alkyl)amine, followed by cyclization of the product thus produced in the presence of a cyclizing agent such as acetic anhydride.