183589-01-7

Upstream product

• 71643-66-8 4-chloro-2-iodo phenol 
• 75-36-5 acetyl chloride 
• 533-58-4 2-Iodophenol 
• 108-24-7 acetic anhydride 
• 95-85-2 2-hydroxy-5-chloro-aniline 
• 116568-33-3 acetic acid-(2-dichloroiodanyl-phenyl ester) 

Downstream Products

• 504422-01-9 acetic acid 4-chloro-2-pent-1-ynyl-phenyl ester 
• 1354728-91-8 4-chloro-2-ethynylphenyl acetate 
• 1354728-61-2 dimethyl 2-(2-acetoxy-5-chlorophenyl)cycloprop-2-ene-1,1-dicarboxylate 
• 1354728-62-3 ethyl 2-(2-acetoxy-5-chlorophenyl)-1-(phenylsulfonyl)cycloprop-2-enecarboxylate 
• 1354728-80-5 dimethyl 2-(5-phenylbenzofuran-3-yl)malonate 
• 1354728-81-6 dimethyl 2-(5-(4-methoxyphenyl)benzofuran-3-yl)malonate 
• 183589-11-9 Acetic acid 4-chloro-2-phenylethynyl-phenyl ester 

Relevant academic research and scientific papers

Benzofurans or isochromenes via the ring-opening cyclization of cyclopropene derivatives with organolithiums

A new and efficient approach to benzocycles from cyclopropene derivatives is described. Deprotection by organolithiums and subsequent ring-opening cyclization of the related 2-cyclopropenyl phenyl or benzyl acetates generated benzofurans and isochromenes in one pot.

Chemistry of aminophenols. Part 3: First synthesis of nitrobenzo[b]furans via a coupling-cyclization approach

The first synthesis of 4-, 5-, and 6-nitrobenzo[b]furans has been achieved via the Sonogashira cross-coupling reaction of 2-iodonitrophenol acetates prepared from commercially available and inexpensive 2-aminonitrophenols. The obtained 2-alkynylnitropheno