183676-87-1Relevant academic research and scientific papers
Expanded scope of heterocyclic biaryl synthesis via a palladium-catalysed thermal decarboxylative cross-coupling reaction
Kissane, Marie,McNamara, Orla A.,Mitchell, David,Coppert, David M.,Moynihan, Humphrey A.,Lorenz, Kurt T.,Maguire, Anita R.
experimental part, p. 403 - 405 (2012/02/02)
The palladium-catalysed decarboxylative cross-coupling of heterocyclic aromatic carboxylates and aryl halides is described. The cross-coupling proceeds under relatively mild conditions using catalytic Pd(0) and tetrabutylammonium bromide (TBAB). Utilizing
A practical synthesis of biaryls via a thermal decarboxylative Pd-catalyzed cross-coupling reaction operating at moderate temperature
Mitchell, David,Coppert, David M.,Moynihan, Humphrey A.,Lorenz, Kurt T.,Kissane, Marie,McNamara, Orla A.,Maguire, Anita R.
scheme or table, p. 981 - 985 (2011/12/15)
The palladium-catalyzed decarboxylative cross-coupling of aminothiophene carboxylate and 1-bromo-4-chlorobenzene to produce 3-amino-2-(4-chlorophenyl) thiophene (2) is described. The cross-coupling proceeds under relatively mild conditions using catalytic Pd(0) and TBAB. Through use of a mixed-solvent system of DMF and NMP, it was possible to operate the cross-coupling system at 80 °C. An assessment of carbon dioxide liberation, which provides insight into the reaction operating parameters, is also discussed.
Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient
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, (2008/06/13)
The substituted thiophene derivative of the invention which is represented by the general formula (1) has a broad disease spectrum for a pathogenic fungus of various crops, exhibits an excellent controlling effect on disease such as gray mold, powdery mil
