183676-97-3Relevant articles and documents
Microbial whole cell-catalyzed desymmetrization of prochiral malonamides: Practical synthesis of enantioenriched functionalized carbamoylacetates and their application in the preparation of unusual α-amino acids
Zhang, Li-Bin,Wang, De-Xian,Wang, Mei-Xiang
body text, p. 5604 - 5609 (2011/08/10)
Catalyzed by Rhodococcus erythropolis AJ270, an amidase-containing microbial whole cell catalyst, under very mild conditions, a number of functionalized prochiral malonamides underwent enantioselective desymmetrization reaction to afford high yield of car
Practical synthesis of optically active α,α-disubstituted malonamic acids through asymmetric hydrolysis of malonamide derivatives with Rhodococcus sp. CGMCC 0497
Wu, Zhong-Liu,Li, Zu-Yi
, p. 2479 - 2482 (2007/10/03)
A variety of α,α-disubstituted malonamides undergo enantioselective hydrolysis with Rhodococcus sp. CGMCC 0497 to give challenging enantiopure α,α-disubstituted malonamic acids with up to >99% enantiomeric excesses and 98% chemical yields. The enantiosele
