183859-96-3

Upstream product

• 117582-62-4 1-bromo-2-formyl-3,4-dihydronaphthalene 
• 536-74-3 phenylacetylene 
• 3262-03-1 1-chloro-2-formyl-3,4-dihydronaphthalene 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 

Downstream Products

• 14385-54-7 phenyl-2 naphto<2,1-b>furanne 
• 1207093-69-3 C₁₉H₁₄O₂ 
• 183860-04-0 4-Nitro-3-phenyl-1-(1-phenylethynyl-3,4-dihydro-naphthalen-2-yl)-butan-1-one 
• 183860-07-3 4-Nitro-1-(1-phenylethynyl-3,4-dihydro-naphthalen-2-yl)-pentan-1-one 
• 183860-08-4 3-Phenyl-5-(1-phenylethynyl-3,4-dihydro-naphthalen-2-yl)-3,4-dihydro-2H-pyrrole 1-oxide 
• 183860-11-9 2-Methyl-5-(1-phenylethynyl-3,4-dihydro-naphthalen-2-yl)-3,4-dihydro-2H-pyrrole 1-oxide 
• 183859-99-6 1-(1-Phenylethynyl-3,4-dihydro-naphthalen-2-yl)-ethanone 
• 183859-97-4 1-(1-Phenylethynyl-3,4-dihydro-naphthalen-2-yl)-ethanol 

Relevant academic research and scientific papers

Microwave assisted [RuCl2(p-cymene)2]2 catalyzed regioselective endo-tandem cyclization involving imine and alkyne activation: An approach to benzo[4,5]imidazo[2,1-a]pyridine scaffold

A microwave assisted efficient route to the synthesis of benzimidazole fused heterocycles through metal catalyzed endo-cyclization strategy involving imine and alkyne activation has been developed. In the presence of [RuCl 2(p-cymene)2/su

Copper-catalyzed addition of water affording highly substituted furan and unusual formation of naphthofuran ring from 3-(1-alkenyl)-2-alkene-1-al

We have developed a novel one-pot reaction to generate highly substituted furan through the addition of water followed by oxidation and unusual cyclization to naphthofuran ring under the same reaction condition.

Synthesis of pyridine-fused ring systems from β-chloroacroleins: A comparison of three different pathways

Three different pathways for the access of pyridine-fused ring systems are described: 1) a Sonogashira coupling of β-chloroacroleins followed by cyclization of the corresponding imines; 2) the same coupling reaction followed by cyclization of the corresponding oximes; and 3) a palladium-catalyzed iminoannulation of internal alkynes.

Synthetic applications of conjugated nitrones, 5. A novel entry to the 13-azasteroid system

A synthetic approach to 13-azasteroid and C-nor-13-azasteroid derivatives (type 17/18) as well as to the 4,13-diaza analogues 27/28 is described. For the construction of the tetracyclic compounds precursors with preformed rings A, B and D containing a conjugated nitrone system were used (16/26). These were prepared from the annulated cyclohexenones 10/ 20a, b in six steps according to slightly modified standard procedures. The failure in obtaining the terminal silyl alkynes 15b by Michael addition of the enolate of 14b to nitrostyrene is explained on the basis of a strong Si-O complexation. After replacement of the trimethylsilyl substituent by the sterically more demanding triisopropylsilyl group the formation of 15c was accomplished as expected. Upon thermally induced 1,7-cyclization of the nitrones 16/26 a multistep rearrangement of the primary cycloallenic intermediates takes place resulting in the formation of the corresponding 6,6,6,5- and 6,6,5,5-ring steroids (17/27 and 18/28) in 55-86% yield. VCH Verlagsgesellschaft mbH, 1996.