183892-47-9

Upstream product

• 162052-67-7 1-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-hydroxymethyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 139925-90-9 1-[(2R,4S,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-5-hydroxymethyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 594-19-4 tert.-butyl lithium 
• 162052-68-8 3'-O-tert-Butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-formyl-thymidin 

Downstream Products

• 183892-70-8 5'-O-(4,4'-Dimethoxytrityl)-4'-C-(2,2-dimethylpropanoyl)thymidine 

Relevant academic research and scientific papers

165. Synthesis of 4′-C-acylated thymidines

Two synthetic pathways towards 4′-C-acylthymidines are presented. These modified mononucleosides are precursors of the 2′-deoxyribonucleotide 4′-C-radical. They were converted into their corresponding 3′-O-[(2-cyanoethyl) N,N-diisopropylphosphoramidites]