183959-08-2Relevant articles and documents
Synthesis and antiviral activity of acyclic analogues of 1,5-anhydrohexitol nucleosides using Mitsunobu reaction
Hossain, Nafizal,Rozenski, Jef,De Clercq, Erik,Herdewijn, Piet
, p. 13655 - 13670 (1996)
Starting from protected hexenetriol, acyclic analogues of the 1,5-anhydrohexitol nucleosides were synthesized. The reaction sequence involved a stereoselective Sharpless dihydroxylation and a Mitsunobu-type alkylation of the nucleoside bases. The compounds did not show antiviral activity.