183989-95-9Relevant academic research and scientific papers
Synthesis of indoles and quinolones by sequential Wittig and Heck reactions
Latham, Elliot J.,Stanforth, Stephen P.
, p. 2059 - 2063 (2007/10/03)
Trifluoroacetamido derivatives 18a-c and 19a-c react with phosphorane 2 in boiling toluene to give the corresponding enamines 12a-c and 13a-c respectively which are precursors of the trifluoromethylated indoles 14a-c and quinolones 15a-c.
Synthesis of indoles and quinolones by sequential Wittig and Heck reactions
Latham, Elliot J.,Stanforth, Stephen P.
, p. 2253 - 2254 (2007/10/03)
N-Trifluoroacetylanilines 6 and 7 undergo a Wittig reaction with phosphorane 2 (R = Et) giving enamine derivatives 9 and 10 respectively which are precursors to indoles 4 and quinolones 5.
