183989-84-6

Basic information

• Product Name: 4-nitro-2-iodo-trifluoroacetanilide
• Synonyms: 4-nitro-2-iodo-trifluoroacetanilide
• CAS NO: 183989-84-6
• Molecular Weight: 360.031
• Mol File: 183989-84-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-nitro-2-iodo-trifluoroacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitro-2-iodo-trifluoroacetanilide(183989-84-6)
• EPA Substance Registry System: 4-nitro-2-iodo-trifluoroacetanilide(183989-84-6)

Safety Data

• Hazardous Substances Data: 183989-84-6(Hazardous Substances Data)

Upstream product

• 6293-83-0 2-iodo-4-nitrophenylamine 
• 407-25-0 trifluoroacetic anhydride 
• 76-05-1 trifluoroacetic acid 

Downstream Products

• 6293-83-0 2-iodo-4-nitrophenylamine 
• 183989-95-9 (E)-4,4,4-Trifluoro-3-(2-iodo-4-nitro-phenylamino)-but-2-enoic acid ethyl ester 
• 408523-59-1 2,4-dichloro-6-nitroquinoline 
• 17420-30-3 5-nitroanthranilonitrile 
• 503534-46-1 4-nitro-2-[(trimethylsilyl)ethynyl]aniline 
• 125600-42-2 2-amino-5-nitrophenylacetylene 
• 37404-51-6 N-(2-cyano-4-nitro-phenyl)-2,2,2-trifluoro-acetamide 

Relevant articles and documents

PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS

Disclosed are compounds of formula (I), and pharmaceutically acceptable salts thereof, which are inhibitors of the complement system. Also provided are pharmaceutical compositions comprising such a compound, and methods of using the compounds and compositions in the treatment or prevention of a disease or condition characterized by aberrant complement system activity.

Synthesis of indoles and quinolones by sequential Wittig and Heck reactions

Trifluoroacetamido derivatives 18a-c and 19a-c react with phosphorane 2 in boiling toluene to give the corresponding enamines 12a-c and 13a-c respectively which are precursors of the trifluoromethylated indoles 14a-c and quinolones 15a-c.