184488-19-5 Usage
General Description
(S)-2-((2-FLUOROPHENOXY)METHYL)OXIRANE, also known as (S)-Fluoxetine epoxide, is a chemical compound that is used in the synthesis of pharmaceuticals. It is an epoxide, which is a type of organic compound containing a three-membered ring with oxygen. This particular compound contains a fluorophenoxy group, which consists of a benzene ring connected to a fluorine atom and a methoxy group. It is commonly used as an intermediate in the production of the antidepressant medication fluoxetine, also known as Prozac. (S)-2-((2-FLUOROPHENOXY)METHYL)OXIRANE is an important building block in the pharmaceutical industry and is used in the synthesis of various medications for the treatment of mental health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 184488-19-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,4,8 and 8 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 184488-19:
(8*1)+(7*8)+(6*4)+(5*4)+(4*8)+(3*8)+(2*1)+(1*9)=175
175 % 10 = 5
So 184488-19-5 is a valid CAS Registry Number.
184488-19-5Relevant articles and documents
Parallel synthesis of 3-aryloxy-2-propanolamines and evaluation as dual affinity 5-HT(1A) and 5-HT re-uptake ligands
Van Niel, Monique B.,Beer, Margaret S.,Castro, Jose L.,Cheng, Susan K.F.,Evans, David C.,Heald, Anne,Hitzel, Laure,Hunt, Peter,Mortishire-Smith, Russell,O'Connor, Desmond,Watt, Alan P.,MacLeod, Angus M.
, p. 3243 - 3248 (1999)
A solution phase synthesis for the preparation of 3-aryloxy-2-propanolamine libraries has been developed. This resulted in the identification of 5 as a ligand with dual affinity for 5-HT(1A) and serotonin re-uptake receptors which shows excellent pharmacokinetic parameters.
Enantioselective parallel synthesis using polymer-supported chiral Co(salen) complexes
Peukert, Stefan,Jacobsen, Eric N.
, p. 1245 - 1248 (2008/02/09)
(matrix presented) The kinetic resolution of epoxides with phenols catalyzed by a polymer-supported Co(salen) complex is applied to the first enantioselective catalytic synthesis of parallel libraries. The corresponding 1-aryloxy-2-alcohols are obtained i
