184532-45-4 Usage
Chiral compound
Contains a phenylmethylamino group and a dimethylsilyloxy group, with an (R)-enantiomer that is useful in chiral separation techniques and as a building block in the synthesis of pharmaceuticals and other complex organic compounds.
Uses
Commonly used as a reagent in organic synthesis and as a chiral auxiliary in asymmetric synthesis.
Pharmacological properties
Has been studied for its potential antiviral and anticancer effects.
Check Digit Verification of cas no
The CAS Registry Mumber 184532-45-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,5,3 and 2 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 184532-45:
(8*1)+(7*8)+(6*4)+(5*5)+(4*3)+(3*2)+(2*4)+(1*5)=144
144 % 10 = 4
So 184532-45-4 is a valid CAS Registry Number.
184532-45-4Relevant academic research and scientific papers
Enantiodivergent synthesis of 2-hydroxymethyl-3-hydroxy-4-nitro-pyrrolidines through tandem Michael-Henry reaction using L-serine as the chiral educt
Barco, Achille,Benetti, Simonetta,De Risi, Carmela,Pollini, Gian P.,Romagnoli, Romeo,Zanirato, Vinicio
, p. 7599 - 7602 (2007/10/03)
By utilizing L-serine, both enantiomers of all trans 2-hydroxymethyl-3-hydroxy-4-nitro-pyrrolidine were efficiently prepared through tandem Michael-Henry methodology. Their stereochemistry has been assigned through conversions of one of them to trans 2-hydroxymethyl-3-hydroxypyrrolidine, a naturally occurring compound recently is isolated from Castanospermum australe.
