184532-44-3

Usage

Uses

Used in Organic Synthesis:
L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-(phenylmethyl)-, methyl ester is used as a building block in organic synthesis for creating more complex molecules. Its unique structure, featuring a methyl ester, phenylmethyl group, and dimethylsilyl group, allows for a wide range of chemical reactions and the formation of various compounds.
Used in Chemical Research:
In the field of chemical research, L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-(phenylmethyl)-, methyl ester serves as a valuable compound for studying the properties and behavior of different functional groups. Its structure allows researchers to investigate the reactivity and stability of the methyl ester, phenylmethyl, and dimethylsilyl groups, as well as their interactions with other molecules.
Used in Pharmaceutical Industry:
L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-(phenylmethyl)-, methyl ester may have potential applications in the pharmaceutical industry for the development of new drugs. Its unique structure and functional groups can be utilized to design and synthesize novel drug candidates with specific therapeutic properties. L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-(phenylmethyl)-, methyl
ester's potential use in drug development is an area of ongoing research and exploration.

Upstream product

• 98642-61-6 (2S)-2-amino-3-(tert-butyldimethylsilanyloxy)propionic acid methyl ester 
• 100-52-7 benzaldehyde 
• 100-39-0 benzyl bromide 
• 1010385-29-1 C₁₈H₃₁NO₃Si 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 352530-50-8 methyl (S)-3-(tert-butyldimethylsilyloxy)-2-(dibenzylamino)propanoate 
• 123639-56-5 (S)-N-benzylserine methyl ester 

Downstream Products

• 209266-12-6 (S)-2-(Benzyl-tert-butoxycarbonyl-amino)-3-(tert-butyl-dimethyl-silanyloxy)-propionic acid methyl ester 
• 192655-86-0 methyl (S)-2-(allylbenzylamino)-3-(tert-butyldimethylsilyloxy)propionate 
• 184758-54-1 (2R,3R,4R)-1-Benzyl-2-hydroxymethyl-4-nitro-pyrrolidin-3-ol 
• 184532-49-8 (2R,3S,4S)-1-Benzyl-2-hydroxymethyl-4-nitro-pyrrolidin-3-ol 
• 184532-46-5 (S)-2-Benzylamino-3-(tetrahydro-pyran-2-yloxy)-propan-1-ol 
• 121686-87-1 (2R,3S)-N-benzyl-3-hydroxy-2-hydroxymethylpyrrolidine 
• 121686-90-6 (2R,3R)-N-benzyl-2-(hydroxymethyl)-3-hydroxypyrrolidine 
• 214632-89-0 (Z)-(3S,7R)-7-Benzylamino-8-(tert-butyl-dimethyl-silanyloxy)-oct-5-en-3-ol 
• 214632-82-3 Benzyl-[(S)-1-(tert-butyl-dimethyl-silanyloxymethyl)-2-hydroxy-but-3-enyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Selective C-N bond oxidation: demethylation of N-methyl group in N-arylmethyl-N-methyl-α-amino esters utilizing N-iodosuccinimide (NIS)

Demethylation of N-methyl group in N-methyl-N-arylmethyl-α-amino esters was accomplished by the oxidation of the amino group using the N-iodosuccinimide (NIS)/acetonitrile system followed by treatment with O-methylhydroxylamine hydrochloride. This combina

Synthesis of bicyclic cyclopropylamines from amino acid derivatives

The synthesis of novel [3.1.0] bicyclic cyclopropylamines from differently substituted amino acids using Ti(II)-mediated coupling and the extension of this methodology to provide [4.1.0] systems is described.

A tuneable method for N-debenzylation of benzylamino alcohols

(Chemical Equation Presented) N-lodosuccinmide provides a mild, convenient, and tuneable reagent for the selective mono- or didebenzylation in representative, multifunctionalized carbohydrate and amino acid derived N-dibenzylamines with neighboring O-func

1,5-asymmetric induction in addition reaction of aldehydes with chiral allyltitaniums having an amino group at the stereogenic center. Synthesis of optically active 2,6-cis-disubstituted piperidines

Chiral allyltitaniums prepared from cyclic carbamate of optically active 4-aminoalk-1-en-3-ols and a Ti(O-i-Pr)4/2i-PrMgCl reagent react with aldehydes with good to excellent regio- and stereoselectivity to afford optically active 1.5-amino alcohols, from which optically active 2,6-cis- disubstituted piperidines are synthesized.

Enantiodivergent synthesis of 2-hydroxymethyl-3-hydroxy-4-nitro-pyrrolidines through tandem Michael-Henry reaction using L-serine as the chiral educt

By utilizing L-serine, both enantiomers of all trans 2-hydroxymethyl-3-hydroxy-4-nitro-pyrrolidine were efficiently prepared through tandem Michael-Henry methodology. Their stereochemistry has been assigned through conversions of one of them to trans 2-hydroxymethyl-3-hydroxypyrrolidine, a naturally occurring compound recently is isolated from Castanospermum australe.