1846-18-0Relevant articles and documents
Radical hydroalkylation and hydroacylation of alkenes by the use of benzothiazoline under thermal conditions
Akiyama, Takahiko,Uchikura, Tatsuhiro,Toda, Mitsuhiro,Mouri, Toshiki,Fujii, Tatsuya,Moriyama, Kaworuko,Ibanez, Ignacio
, p. 12715 - 12723 (2020)
The hydroalkylation and hydroacylation of electrondeficient alkenes proceeded smoothly by using benzothiazoline derivatives as radical-transfer reagents under thermal conditions without light irradiation or any additive. Both benzyl and benzoyl moieties were transferred efficiently.
C(sp3)-H functionalizations of light hydrocarbons using decatungstate photocatalysis in flow
Deng, Yuchao,Fagnoni, Maurizio,Guthrie, Duncan,Laudadio, Gabriele,No?l, Timothy,Nun?, Manuel,Ravelli, Davide,Sun, Yuhan,Wal, Klaas Van Der
, p. 92 - 96 (2020/09/03)
Direct activation of gaseous hydrocarbons remains a major challenge for the chemistry community. Because of the intrinsic inertness of these compounds, harsh reaction conditions are typically required to enable C(sp3)-H bond cleavage, barring potential applications in synthetic organic chemistry. Here, we report a general and mild strategy to activate C(sp3)-H bonds in methane, ethane, propane, and isobutane through hydrogen atom transfer using inexpensive decatungstate as photocatalyst at room temperature. The corresponding carbon-centered radicals can be effectively trapped by a variety of Michael acceptors, leading to the corresponding hydroalkylated adducts in good isolated yields and high selectivity (38 examples).
One-pot synthesis of malononitriles by free radical reactions of ylidenemalononitrile with Et3B and iodoalkane in a water-ether biphase medium
Tu, Zhijay,Lin, Chunchi,Jang, Yaochung,Jang, Yeong-Jiunn,Ko, Shengkai,Fang, Hulin,Liu, Ju-Tsung,Yao, Ching-Fa
, p. 6133 - 6137 (2007/10/03)
The one-pot synthesis of malononitrile derivatives 4, 6, and 7 in moderate to high yields by the reaction of ylidenemalononitriles 3, prepared in situ from carbonyl compounds 1 and malononitrile 2 in the presence of ammonium acetate in aqueous solution at
