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Nigracin, a natural product derived from the thermophile Thermomonospora fusca, is a member of the angucycline group of antibiotics. It features a unique tetracyclic core structure and demonstrates potent antibacterial activity against a range of pathogens, including multidrug-resistant strains. Nigracin operates by inhibiting bacterial DNA gyrase, a crucial enzyme for DNA replication and transcription. Its distinctive chemical structure and strong antibacterial properties position Nigracin as a promising candidate for further research and potential therapeutic applications, particularly in the development of new antibiotics and the treatment of bacterial infections.

18463-25-7

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18463-25-7 Usage

Uses

Used in Pharmaceutical Industry:
Nigracin is used as an antibacterial agent for its ability to combat a variety of bacterial pathogens, including those that are multidrug-resistant. Its mechanism of action involves the inhibition of bacterial DNA gyrase, which is essential for DNA replication and transcription, thereby disrupting the bacteria's ability to proliferate and survive.
Used in Antibiotic Development:
Nigracin serves as a lead compound in the development of new antibiotics. Its unique tetracyclic core structure and potent antibacterial activity make it a valuable asset in the creation of novel therapeutic agents to address the growing challenge of antibiotic resistance.
Used in Research:
Nigracin is utilized in scientific research to explore its potential applications and mechanisms of action further. Studies on Nigracin can contribute to a better understanding of its antibacterial properties and may lead to the discovery of new strategies for combating bacterial infections.

Check Digit Verification of cas no

The CAS Registry Mumber 18463-25-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,4,6 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 18463-25:
(7*1)+(6*8)+(5*4)+(4*6)+(3*3)+(2*2)+(1*5)=117
117 % 10 = 7
So 18463-25-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H22O9/c21-9-12-8-13(22)6-7-14(12)28-20-18(25)17(24)16(23)15(29-20)10-27-19(26)11-4-2-1-3-5-11/h1-8,15-18,20-25H,9-10H2/t15-,16-,17+,18-,20-/m1/s1

18463-25-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[4-hydroxy-2-(hydroxymethyl)phenoxy]oxan-2-yl]methyl benzoate

1.2 Other means of identification

Product number -
Other names poliothrysoside

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18463-25-7 SDS

18463-25-7Upstream product

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