184643-10-5Relevant articles and documents
Enantiomeric resolution of fluorous mixture by chiral CD columns: Asymmetric reduction of a mixture of fluorous ketones
Nakamura, Yutaka,Takeuchi, Seiji,Okumura, Kazuo,Ohgo, Yoshiaki,Matsuzawa, Hiroshi,Mikami, Koichi
, p. 6221 - 6225 (2007/10/03)
Asymmetric reduction of a mixture of four fluorous ketone analogues was carried out with (R)-oxazaborolidine as a catalyst. The fluorous mixture products were resolved by a reverse phase HPLC with chiral β-cyclodextrin column to result in good separation of the enantiomers.