184705-11-1

Upstream product

• 184705-08-6 3-(carbomethoxy)-2-ethyl-1-(phenylmethyl)-5-methoxyindole 
• 30414-53-0 methyl propanoyl acetate 
• 100-46-9 benzylamine 
• 184705-03-1 1-benzyl-2-ethyl-5-hydroxy-1H-indole-3-carboxylic acid methyl ester 
• 184705-06-4 methyl 3-(benzylamino)pent-2-enoate 
• 1620230-78-5 C₃₃H₃₅NO₄Si 
• 1620230-80-9 C₃₅H₃₉NO₂Si 
• 16077-10-4 N-benzyl-5-methoxyisatin 
• 1620230-76-3 C₂₁H₂₃NO₅ 
• 1620230-77-4 1-benzyl-3-hydroxy-3-(hydroxymethyl)-5-methoxyindolin-2-one 
• 1439598-96-5 1-benzyl-3-hydroxy-5-methoxyindolin-2-one 

Downstream Products

• 164123-34-6 3-(amidomethyl)-2-ethyl-1-(phenylmethyl)-5-hydroxyindole 
• 164084-29-1 3-(amidomethyl)-2-ethyl-1-(phenylmethyl)-5-methoxyindole 
• 164083-83-4 dimethyl [3-[[3-(amidomethyl)-2-ethyl-1-(phenylmethyl)-indol-5-yl]oxy]propyl]phosphonate 
• 164083-79-8 ethyl [4-[3-(amidomethyl)-2-ethyl-1-(phenylmethyl)-indol-5-yl]oxy]butanoate 
• 1026933-81-2 C₂₈H₄₃N₂O₅PSi₂ 
• 184705-14-4 3-(cyanomethyl)-2-ethyl-1-(phenylmethyl)-5-methoxyindole 

Relevant academic research and scientific papers

Facile regiospecific synthesis of 2,3-disubstituted indoles from isatins

A facile regiospecific synthesis of 2,3-disubstituted indoles from isatins has been developed. Nucleophilic addition of Grignard reagents to commercially available isatins, followed by reduction with borane, afforded an array of structurally diverse 2,3-disubstituted indoles in moderate to good yields. The method described herein represents a novel and very simple approach to synthesize various 2,3-disubstituted indoles, extremely important structural motifs in the pharmaceutical industry and medicinal chemistry. This journal is the Partner Organisations 2014.

Synthesis of indomethacin analogues for evaluation as modulators of MRP activity

Synthesis of a range of indomethacin analogues, required for investigation in combination toxicity assays, bearing both N-benzyl and N-benzoyl groups, is described. Copyright