18471-74-4Relevant academic research and scientific papers
2-Pyridyl and 3-pyridylzinc bromides: direct preparation and coupling reaction
Kim, Seung-Hoi,Rieke, Reuben D.
scheme or table, p. 3135 - 3146 (2010/06/13)
A facile synthetic approach to the direct preparation of 2-pyridyl and 3-pyridylzinc bromides has been demonstrated using Rieke zinc with 2-bromopyridine and 3-bromopyridine, respectively. A variety of different electrophiles have been coupled with the resulting organozinc reagents to give the corresponding cross-coupling products in moderate to good yields.
Coupling reactions with haloaromatic amines and alcohols for a practical synthetic route to 2-substituted aminophenyl and hydroxyphenyl pyridines
Kim, Seung-Hoi,Rieke, Reuben D.
supporting information; experimental part, p. 6985 - 6988 (2010/02/27)
A practical synthetic route to 2-substituted aminophenyl and hydroxyphenyl pyridines has been developed. It has been accomplished by the cross-coupling reactions of readily available 2-pyridylzinc bromides with haloaromatic amines and alcohols under mild
