1848-65-3

Upstream product

• 96-20-8 2-aminobutanol 
• 5461-83-6 N-nitro-N'-phenyl-guanidine 
• 6189-18-0 1-(1-hydroxymethyl-propyl)-3-phenyl-urea 
• 103-71-9 phenyl isocyanate 
• 622-16-2 1,3-Diphenylcarbodiimide 
• 254900-21-5 1-(1-hydroxybutan-2-yl)-3-phenylthiourea 

Relevant academic research and scientific papers

A mild cyclodesulfurization of N-(2-hydroxyethyl)-N′-phenylthioureas to 2-phenylamino-2-oxazolines using TsCl/NaOH

An efficient synthesis of 2-phenylamino-2-oxazolines 3 via cyclodesulfurization of N-(2-hydroxyethyl)-N′-phenylthioureas 2 by a one-pot reaction using p-toluenesulfonyl chloride (TsCl) and NaOH in very good yields is described.

Investigation of the Mitsunobu reaction of N-(2-hydroxyethyl)-N'- phenyl-ureas

The Mitsunobu reaction of N-(2-hydroxyethyl)-ureas 1 using PPh3 and EtO2CN=NCO2Et led to the mixture of N- and O-alkylation products or a single isomer depending on the substrates.