18480-53-0

Basic information

• Product Name: 3,4-DICHLOROISOTHIAZOLE-5-CARBOXYLIC ACID
• Synonyms: 3,4-DICHLOROISOTHIAZOLE-5-CARBOXYLIC ACID;5-Isothiazolecarboxylic acid, 3,4dichloro;3,4-Dichloro-5-isothiazolecarboxylic acid;3,4-DICHLORO-5-ISOTHIAZOLE-3-CARBOXYLIC ACID;3,4-dichloro-1,2-thiazole-5-carboxylic acid;Isotianil;3,4-Dichloro-5-carboxyisothiazole
• CAS NO: 18480-53-0
• Molecular Formula: C₄HCl₂NO₂S
• Molecular Weight: 198.03
• Mol File: 18480-53-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 175-177°C
• Boiling Point: 205.9 °C at 760 mmHg
• Flash Point: 78.4 °C
• Appearance: /
• Density: 1.824
• Vapor Pressure: 0.147mmHg at 25°C
• Refractive Index: 1.646
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.74±0.28(Predicted)
• CAS DataBase Reference: 3,4-DICHLOROISOTHIAZOLE-5-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DICHLOROISOTHIAZOLE-5-CARBOXYLIC ACID(18480-53-0)
• EPA Substance Registry System: 3,4-DICHLOROISOTHIAZOLE-5-CARBOXYLIC ACID(18480-53-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 18480-53-0(Hazardous Substances Data)

Usage

General Description

3,4-Dichloroisothiazole-5-carboxylic acid is a chemical compound that belongs to the isothiazole family. It is a white to pale yellow crystalline powder with a pungent odor. 3,4-DICHLOROISOTHIAZOLE-5-CARBOXYLIC ACID is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in the manufacturing of dyes, pigments, and other organic compounds. Additionally, 3,4-dichloroisothiazole-5-carboxylic acid has antimicrobial properties and is used as a preservative in various industrial and consumer products. However, it is important to handle this compound with caution as it is known to be a skin and eye irritant.

InChI:InChI=1/C4HCl2NO2S/c5-1-2(4(8)9)10-7-3(1)6/h(H,8,9)

Upstream product

• 18480-52-9 3,4-dichloro-5-cyanoisothiazole 

Relevant articles and documents

Synthesis, Structure, and Spectroscopic Properties of Isotianil as a Bactericide

Abstract: Isotianil [N-(2-cyanophenyl)-3,4-dichloro-1,2-thiazole-5-carboxamide] has beensynthesized in a good yield with high purity by reaction of the key intermediateproduct, N-(2-carbamoylphenyl)-3,4-dichloro-1,2-thiazole-5-carboxamide, withthionyl chloride in N,N-dimethylformamide at 60°C. The structure of isotianil wasstudied by X-ray analysis. It crystallized in triclinic space group P1 with a =11.459(3), b = 12.632(3), c = 22.528(5) ?, α = 78.897(3), β = 81.730(3), γ =71.493(3)°, Z = 10.

Isothiazolecarboxylic acid derivatives, rice blast control agents containing the same as active ingredients, and rice blast control method applying the control agents

Application of a rice blast control agent containing an isothiazolecarboxylic acid derivative of the below-described formula, which shows excellent activity against rice blast (Pyricularia oryzae) in rice cultivation, to the water surface of a paddy rice field results in the absorption of the derivative through roots of rice plants, so that the resistance of the rice plants can be enhanced. STR1 wherein R1 and R2 independently mean a hydrogen or halogen atom or a particular group, and Y stands for an OR3 group (R3 being a hydrogen or alkali metal atom or a particular group), an NHR4 group (R4 being a hydrogen atom or a particular group), or a morpholino group.

1,2,3-Thiadiazole-2-id derivatives, process for making the same and composition containing the same having a growth regulating activity for plants

1,2,3-Thiadiazole-2-id-derivative of the formula STR1 in which R1 is hydrogen or alkyl which may be substituted in one or several places by oxygen or sulfur and wherein R1 has the meaning as given in the attached specification and wherein X is oxygen or sulfur and B is a univalent metal atom. The compounds have properties suited for controlling the natural growth and natural development of plants and in addition have a superior defoliating property.