185-60-4

Usage

Uses

Used in Pharmaceutical Industry:
1-Oxaspiro[2.4]heptane is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be chemically modified and incorporated into complex molecular structures.
Used in Fragrance Industry:
1-Oxaspiro[2.4]heptane is used as a component in the creation of fragrances due to its characteristic odor and ability to blend well with other aromatic compounds.
Used in Flavoring Industry:
1-Oxaspiro[2.4]heptane is used as a flavoring agent in the food and beverage industry, where its unique properties can enhance or modify the taste of products.
It is important to handle 1-Oxaspiro[2.4]heptane with care, as it may pose certain health and safety hazards if not used properly.

Upstream product

• 1528-30-9 methylenecyclopentane 
• 120-92-3 cyclopentanone 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 186581-53-3 diazomethane 
• 7732-18-5 water 

Downstream Products

• 1528-30-9 methylenecyclopentane 
• 124615-81-2 2-phenylselenocyclopentanol 
• 10316-79-7 (1-aminocyclopentyl)methanol 
• 872-53-7 cyclopentanealdehyde 

Relevant academic research and scientific papers

Selective homologation of ketones and aldehydes with diazoalkanes promoted by organoaluminum reagents

Organoaluminum-promoted single homologation or ring expansion of ketones and aldehydes with diazoalkanes has been described, and among various organoaluminium reagents, exceptionally bulky methylaluminum bis(2,6-di-tert-butyl-4-methylphenoxide) (MAD) is found to be highly effective for the selective homologation of various ketones and aldehydes.

Organoaluminum-Promoted Homologation of Ketones with Diazoalkanes

Organoaluminum-promoted single homologation of aliphatic and aromatic ketones with diazoalkanes has been described, and among various organoaluminum reagents, especially bulky methylaluminum bis(2,6-di-tert-butyl-4-methylphenoxide) (MAD) is found to be highly effective for the selective homologation of various ketones.

Studies on the Autoxidation of Some Monocyclic Olefins

The autoxidations of cyclopentene, cyclohexene, cycloheptene, cyclooctene, cycloocta-1,5-diene, 1-methylcyclopentene, 1-methylcyclohexene, 1-methylcycloheptene, 1-methylcyclooctene, methylene cyclopentene, and methylene cyclohexene with pure oxygen under normal pressure were studied.The epoxides formed were determined gaschromatographically.In most cases also the products of allylic oxidation were analyzed and their structures elucidated after reduction to the corresponding allyl alcohols.The portions of high boiling or polymeric products which could not be detected gaschromatographically and also the real yields of epoxides were determined by balance experiments in the presence of inert internal standards.