124615-81-2

Upstream product

• 5707-04-0 Phenylselenyl chloride 
• 142-29-0 cyclopentene 
• 285-67-6 Cyclopentene oxide 
• 1666-13-3 diphenyl diselenide 
• 645-96-5 Benzeneselenol 
• 1111071-92-1 phenylselenyl zinc chloride 
• 113815-45-5 C₅H₉BrHgO 
• 185-60-4 1-oxaspiro[2.4]heptane 
• 591-50-4 iodobenzene 
• 65-85-0 benzoic acid 
• 98-80-6 phenylboronic acid 
• 62-53-3 aniline 
• 101327-56-4 Se-phenyl(selenothioperoxy)benzoate 

Downstream Products

• 106994-99-4 trans-1-(acrylamido)-2-(phenylseleno)cyclopentane 
• 285-67-6 (1S,5R)-6-Oxa-bicyclo[3.1.0]hexane 
• 106994-89-2 trans-1-(chloroacetamido)-2-(phenylseleno)cyclopentane 

Relevant academic research and scientific papers

Synthesis of β-hydroxy aryl selenides via transition-metal-free three-component reaction of arylamines, elemental selenium, and epoxides

An efficient protocol for the construction of valuable β-hydroxy aryl selenides from easily available arylamines, elemental selenium, and epoxides through a transition-metal-free radical process is described. A wide variety of β-hydroxy aryl selenides were obtained in good to excellent yields with excellent stereo- and regioselectivity. In this reaction, two C-Se bonds can be built along with the cleavage of a C-N and C-O bond, demonstrating the high step economy and efficiency of this approach.

Beta-hydroxyl selenide compound and preparation method

The invention relates to a beta-hydroxyl selenide compound and a preparation method. The preparation method comprises the following steps of: performing cascade reaction in an organic solvent by adopting an epoxy compound and phenylboronic acid as reactio

Beta-hydroxyselenoether compound and preparation method thereof

The invention relates to a beta-hydroxy selenoether compound and a preparation method thereof. In an organic solvent, an epoxy compound and a benzoic acid are used as reaction raw materials, and elemental selenium is used as a selenization reagent for cas

A β- hydroxyl selenium etheration method for synthesizing compound of

The invention relates to a synthetic method of Beta-hydroxyl selenide compound. The method includes: in organic solvent, in the presence of catalyst and alkali, allowing halogenated compound to react with elemental Se and epoxy compound to obtain Beta-hydroxyl selenide compound. The synthetic method has the advantages that reaction is simple, operating is simple, yield is high, the method is a novel one, a novel synthetic route is provided for the synthesis of the Beta-hydroxyl selenide compounds, and the method has good scientific research value and industrial potential.

Copper-Catalyzed Oxirane-Opening Reaction with Aryl Iodides and Se Powder

Using Se powder as the selenating reagent, the copper-catalyzed double C-Se cross-coupling of aryl iodides, epoxides, and elemental selenium has been developed. This strategy provides a straightforward approach to the synthesis of β-hydroxy phenylselenides with excellent regioselectivity of the ring opening reaction. This process proceeds in generally good yields and is compatible with a broad range of functional groups.

Preparation of the first bench-stable phenyl selenolate: An interesting "on water" nucleophilic reagent

In this communication we report the synthesis and the characterization of the first solid and air-stable selenolates, starting from commercially available phenylselenenyl halides and elemental zinc. These reagents were efficiently employed in the ring ope

Lipase-catalyzed resolution of β-hydroxy selenides

Eleven β-hydroxy selenides were kinetically resolved using an immobilized lipase (Amano PS-C II) in toluene in the presence of vinyl acetate at 30 °C. This approach provided, in several cases, both enantiomers in high enantiomeric excess. The role of the size of substituents and the behaviour of cyclic β-hydroxy selenides is also discussed. Enantiopure β-hydroxy selenides are useful building blocks. As an application of this chemistry, enantiopure (1S,2R)-indene oxide was obtained in one step from the proper enantiopure β-hydroxy selenide.

Synthesis of β-hydroxy selenides using benzeneselenol and oxiranes under supramolecular catalysis in the presence of β-cyclodextrin in water

A simple and efficient method for the synthesis of β-hydroxy selenides is reported at room temperature in impressive yields for the first time by the highly the regioselective ring-opening of oxiranes with benzeneselenol in water under supramolecular cata

Tetrathiomolybdate assisted epoxide ring opening with masked thiolates and selenoates: Multistep reactions in one pot

Tetrathiomolybdate provides an easy access to β-hydroxy disulfides, β-hydroxy sulfides, and selenides from epoxides in a tandem, multistep process in one pot. This strategy has been utilized effectively in the construction of thiabicylo[3.2.2]nonane derivative 24.