185030-08-4

Usage

Chemical structure

A complex chemical compound with a dioxolan-4-one ring and various substituents.

Substituents

Consists of a cyclopentenyl, tert-butyl, and phenyl groups attached to the dioxolan-4-one ring.

Optical activity

The compound is optically active, meaning it can rotate plane-polarized light.

Configuration

The compound has a specific configuration of (2S,5S), which refers to the arrangement of atoms in the molecule.

Stereochemistry

The stereochemistry of the compound is important for its potential applications and interactions with other molecules.

Synthetic compound

It is likely a synthetic compound, meaning it is created through chemical synthesis rather than being directly extracted from a natural source.

Potential applications

The compound may have potential applications in the field of organic chemistry, but further information is needed to fully understand its potential.

Further research

Additional information about the compound's properties, reactivity, and potential uses would be necessary to fully understand its potential in various fields.

Upstream product

• 630-19-3 pivalaldehyde 
• 81036-97-7 (2S,5S)-2-tert-butyl-5-phenyl-1,3-dioxolan-4-one 
• 17199-29-0 (S)-Mandelic acid 
• 302842-80-4 (2S,5R)-2-(tert-butyl)-5-phenyl-5-(1-hydroxycyclopentyl)-1,3-dioxolan-4-one 

Downstream Products

• 185030-09-5 (R)-α-(cyclopentyl-1-ene)-α-hydroxyl-α-phenylacetic acid 
• 876863-22-8 methyl (S)-α-(cyclopentyl-1-ene)-α-hydroxy-α-phenylacetate 
• 64471-43-8 (S)-α-cyclopentyl-α-hydroxy-α-phenylacetic acid 
• 860644-54-8 (S)-methyl-α-cyclopentyl-α-hydroxyl-α-phenylacetate 
• 937179-77-6 cis-(2S,5S)-2-(tert-butyl)-5-phenyl-5-cyclopentyl-1,3-dioxolan-4-one 
• 302842-81-5 (S)-α-(cyclopentyl-1-ene)-α-hydroxy-α-phenylacetic acic 

Relevant academic research and scientific papers

Discovery of a Novel Muscarinic Receptor PET Radioligand with Rapid Kinetics in the Monkey Brain

Positron emission tomography (PET), together with a suitable radioligand, is one of the more prominent methods for measuring changes in synaptic neurotransmitter concentrations in vivo. The radioligand of choice for such measurements on the cholinergic sy

Stereoselective synthesis of the optical isomers of a new muscarinic receptor antagonist, HL-031120

We present here a practical stereoselective synthetic method to produce enantiopure isomers of a new muscarinic receptor antagonist, HL-031120 (3-quinuclidinyl-2′-cyclopentyl-2′-hydroxy-2′-phenylacetate, I). Four optical isomers were effectively by stereoselective synthesized using pivaldehyde as steric hindrance agent from the chiral starting material, ( S ) or ( R )-mandelic acid. The isomers were obtained with 70-76% yields in 98-99% e.e. Copyright Taylor & Francis Group, LLC.

Stereoselective synthesis of the optical isomers of a new muscarinic receptor antagonist, quinuclidin-3-yl 2-(cyclopent-1-enyl)-2-hydroxy-2- phenylacetate

The enantiopure isomers of a new muscarinic receptor antagonist, quinuclidin-3-yl 2-(cyclopent-1-enyl)-2-hydroxy-2-phenylacetate were synthesised by a practical stereoselective synthetic method, using pivaldehyde as steric hindrance agent from the chiral starting material, (S) or (R)-mandelic acid. The isomers were obtained with 72-78% yields in 98-99% e.e.

Stereoselective synthesis of 3-azabicyclo[3,3,1]nonan-9α-yl α-(cyclopentyl-1-ene)-α-hydroxy-α-phenylacetate hydrochloride

The isomers of α-(cyclopentyl-1-ene)-α-hydroxy-α- phenylacetic acid esters derived from 3-azabicyclo[3,3,1]nonan-9α-ol ((R)-1 and (S)-1) were obtained in high enantiomeric excess by effective stereoselective synthesis from the chiral starting material, (S

1,4-di-substituted piperidine derivatives

This invention provides novel 1,4-di-substituted piperidine derivatives of the general formula ?I! STR1 and the pharmaceutically acceptable salts thereof, wherein: Ar represents a phenyl group or a five- or six-membered heteroaromatic group having one or two hetero atoms selected from the group consisting of an oxygen atom, a sulfur atom and a nitrogen atom in which one or two optional hydrogen atoms on the ring may be replaced by substituent groups selected from the group consisting of a halogen atom and a lower alkyl group; R1 represents a cycloalkyl group of 3 to 6 carbon atoms or a cycloalkenyl group of 3 to 6 carbon atoms; R2 represents a saturated or unsaturated aliphatic hydrocarbon radical of 5 to 15 carbon atoms; and X represents O or NH. These compounds have selective antagonistic activity against the muscarinic M3 receptors and can hence be used safely with a minimum of side effects.