185097-50-1

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 98-88-4 benzoyl chloride 
• 134218-81-8 5’-O-(tert-butyldimethylsilyl)-2’-deoxy-5-iodouridine 

Downstream Products

• 198008-55-8 Benzoic acid (2R,3S,5R)-2-[(2-cyano-ethoxy)-diisopropylamino-phosphanyloxymethyl]-5-(5-iodo-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 249286-87-1 3'-O-benzoyl-2'-deoxy-5-(8-trifluoracetamidooct-1-ynyl)uridine 5'-(2-cyanoethoxy)-methoxycarbonylmethyl phosphate 
• 249286-85-9 3'-O-benzoyl-2'-deoxy-5-(8-trifluoracetamidooct-1-ynyl)uridine 5'-<(2-cyanoethyl)-N,N-diisopropyl> phosphoramidite 
• 249286-83-7 3'-O-benzoyl-2'-deoxy-5-(8-N-trifluoroacetamido-oct-1-ynyl)-uridine 
• 144872-54-8 3'-O-bezoyl-2'-deoxy-5-iodouridine 

Relevant academic research and scientific papers

Syntheses of inhibitors for the enzyme thymidine 5'-diphosphate-glucose-4,6-dehydratase (EC 4.2.1.46)

Inhibitors of the enzyme thymidine 5'-diphosphate-glucose-4,6-dehydratase (EC 4.2.1.46) were synthesised starting from thymidine, 2-deoxy-uridine and -cytidine. The diphosphate moieties have either been replaced by methylene diphosphonate or phosphoryl hy

Synthesis of a D-lactosyl cluster-nucleoside conjugate

The synthesis of a nucleoside-oligolactoside conjugate, expected to provide site-specific drug delivery to the human liver, is described.