1851-84-9Relevant academic research and scientific papers
From Alkenes to Isoxazolines via Copper-Mediated Alkene Cleavage and Dipolar Cycloaddition
Gao, Mingchun,Gan, Yuansheng,Xu, Bin
supporting information, p. 7435 - 7439 (2019/10/08)
An unprecedented copper-mediated anion transformation is reported, along with selective C= C double bond cleavage and dipolar cycloaddition reaction from simple alkenes and inexpensive copper nitrate. Various transformations demonstrate the generality of this method. Further mechanistic investigation indicates a novel ionic pathway for alkene cleavage and highlights the coeffect of iodide and boric acid as additives on the inhibition of well-documented competitive nitration byproducts.
