1851-92-9Relevant articles and documents
Photochemical oxidation of benzylic primary and secondary alcohols utilizing air as the oxidant
Nikitas, Nikolaos F.,Tzaras, Dimitrios Ioannis,Triandafillidi, Ierasia,Kokotos, Christoforos G.
supporting information, p. 471 - 477 (2020/02/13)
A mild and green photochemical protocol for the oxidation of alcohols to aldehydes and ketones was developed. Utilizing thioxanthenone as the photocatalyst, molecular oxygen from air as the oxidant and cheap household lamps or sunlight as the light source, a variety of primary and secondary alcohols were converted into the corresponding aldehydes or ketones in low to excellent yields. The reaction mechanism was extensively studied.
Synthesis and biological evaluation of C-3 aliphatic coumarins as vitamin K antagonists
Montagut-Romans, Adrien,Boulven, Manon,Jacolot, Ma?wenn,Moebs-Sanchez, Sylvie,Hasco?t, Claire,Hammed, Abdessalem,Besse, Stéphane,Lemaire, Marc,Benoit, Etienne,Lattard, Virginie,Popowycz, Florence
, p. 1598 - 1601 (2017/03/17)
Since the discovery of Warfarin in the 1940s, the design of new warfarin-derived anticoagulants for rodent management has been challenging, with mainly structural modifications performed on the C3 position of the coumarin skeleton. In order to better understand the pharmacomodulation of such derivatives, we have synthesized a family of C3 (linear and branched) alkyl-4-hydroxycoumarins, which led to the identification of compounds 5e and 5f as potential short-term active anticoagulants.
Synthesis of new (R)-secondary carbinols with different structures via enzymatic resolution
Yildiz, Tuelay,Yusufolu, Aye
experimental part, p. 1347 - 1352 (2011/11/29)
The present study deals with the biocatalytic enantioselective synthesis of 19 new chiral alcohols with alkyl (C11-C19) and phenyl, substituted phenyl, heteroaromatic, and naphthyl groups 4a-4z with an (R)-configuration and high enan
