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185434-43-9

4-Piperidineacetic acid, 1-[(3,4-dichlorophenyl)methyl]-, ethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 185434-43-9 Structure

  • Basic information

    1. Product Name: 4-Piperidineacetic acid, 1-[(3,4-dichlorophenyl)methyl]-, ethyl ester
    2. Synonyms:
    3. CAS NO:185434-43-9
    4. Molecular Formula: C16H21Cl2NO2
    5. Molecular Weight: 330.254
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 185434-43-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-Piperidineacetic acid, 1-[(3,4-dichlorophenyl)methyl]-, ethyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-Piperidineacetic acid, 1-[(3,4-dichlorophenyl)methyl]-, ethyl ester(185434-43-9)
    11. EPA Substance Registry System: 4-Piperidineacetic acid, 1-[(3,4-dichlorophenyl)methyl]-, ethyl ester(185434-43-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 185434-43-9(Hazardous Substances Data)

185434-43-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 185434-43-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,4,3 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 185434-43:
(8*1)+(7*8)+(6*5)+(5*4)+(4*3)+(3*4)+(2*4)+(1*3)=149
149 % 10 = 9
So 185434-43-9 is a valid CAS Registry Number.

185434-43-9Relevant articles and documents

Design and synthesis of novel CCR3 antagonists

Gong, Leyi,Hogg, J. Heather,Collier, James,Wilhelm, Robert S.,Soderberg, Carol

, p. 3597 - 3600 (2007/10/03)

As part of our investigation into the development of potent CCR3 antagonists, a series of piperidine analogues was designed and prepared. Exploration of the piperidine core examined both the basicity and the location of a nitrogen, as well as conformational variants. The bicyclo-piperidine 24c was found to be the most potent inhibitor of CCR3 with an IC50 of 0.0082 μM in the binding assay and 0.0024 μM in the chemotaxis assay.

Cyclic amine derivatives-CCR-3 receptor antagonists

-

Page column 63, (2010/01/31)

This invention relates to certain cyclic amine derivatives of Formula (I) that are CCR-3 receptor antagonist, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.

Cyclic amine derivatives- CCR-3 receptor antagonists

-

, (2008/06/13)

This invention relates to certain cyclic amine derivatives of Formula (I) that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.

Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]-1- benzylpiperidine for the dopamine transporter: Effect of different aromatic substitutions on their affinity and selectivity

Dutta, Aloke K.,Coffey, Lori L.,Reith, Maarten E. A.

, p. 35 - 43 (2007/10/03)

Several analogs of the potent and selective dopamine transporter (DAT) ligand 4-[2(diphenylmethoxy)ethyl]-1-benzylpiperidine, 1a, were prepared and biologically evaluated at the dopamine and serotonin transporter (SERT) sites. Several substituents were in

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