18545-45-4

Upstream product

• 142836-42-8 α-chlorohexanal dimethylacetal 
• 67-56-1 methanol 
• 1599-49-1 4-methyl-2-pentyl-1,3-dioxolane 
• 132148-76-6 4-Chlormethyl-2-pentyl-1,3-dioxalan 

Downstream Products

• 14925-60-1 methyl α-chlorohexanoate 
• 158878-29-6 α,α-dichlorohexanamide 
• 62269-33-4 (Z) methyl 2-chloro-2-hexenoate 

Relevant academic research and scientific papers

Trichloroisocyanuric Acid Oxidation of 2-Chloro Aldehyde Acetals to 2-Chloro Acids Esters

2-Chloro acid methyl esters were prepared in good yields treating 2-chloro aldehyde dimethyl acetals with trichloroisocyanuric acid in DMF.Aldehyde dimethyl acetals with the 2-halogen on a tertiary carbon atom were poorly reactive and could be oxidized efficiently only after their transformation into 1,3-dioxolanes.

Methyl α,α-dichloro-esters by oxidation-chlorination of cyclic acetals with trichloroisocyanuric acid

Methyl α-chloro- or α,α-dichloro-esters are obtained in excellent yields by oxidation chlorination of 2-alkyl-4,5-dimethyl-1,3-dioxolanes with trichloroisocyanuric acid.