14925-60-1

Usage

InChI:InChI=1/C7H13ClO2/c1-3-4-5-6(8)7(9)10-2/h6H,3-5H2,1-2H3

Upstream product

• 18545-45-4 Methyl-2,2-dichlorhexanoat 
• 67-56-1 methanol 
• 29671-30-5 2-chlorohexanoic acid 
• 18207-17-5 α-bromohexanal dimethylacetal 
• 106-70-7 methyl hexanoate 
• 142836-42-8 α-chlorohexanal dimethylacetal 
• 186581-53-3 diazomethane 
• 7782-50-5 chlorine 
• 142-61-0 Hexanoyl chloride 
• 32798-42-8 methyl α-butylacetoacetate 

Downstream Products

• 636-36-2 rac-2-hydroxyhexanoic acid 
• 348144-52-5 2-(2,4-dihydroxyphenyl)-4,6-bis(2-hydroxy-4-(1-methoxycarbonylpentoxy)phenyl)-1,3,5-triazine 

Relevant academic research and scientific papers

New free-radical halogenations of alkanes, catalysed by N-hydroxyphthalimide. Polar and enthalpic effects on the chemo- and regioselectivity

Reactions of alkanes with different halogenating systems are compared in order to explore the reactivity of phthalimido-N-oxyl radical in hydrogen abstraction; the importance of polar effects is emphasised.

Electrooxidation of malonate and acetylacetate derivatives in the presence of halide ions

β-Dicarbonyl compounds, such as dimethyl malonate derivatives and methyl acetoacetate derivatives, were electrooxidized in methanol in the presence of halogen ions to afford the corresponding dimethyl α-halomalonates and methyl α-halocarboxylates. Electrooxidation of bis(β-dimethoxycarbonyl) derivatives similarly afforded cyclic compounds and dihalides.

Decyclization of chlorocyclohexanone hydroperoxides under the action of ferrous salts

The decomposition of 2-chloro-, 2,2-dichloro-, and 2,6-dichloro-substituted cyclohexanone hydroperoxides on treatment with ferrous chloride and sulfate to give chloro-substituted aliphatic acids was investigated. A method for the synthesis of 2,6,6-trichlorohexanoic and 2,6,7,11-tetrachlorododecane-1,12-dioic acids was elaborated.

Trichloroisocyanuric Acid Oxidation of 2-Chloro Aldehyde Acetals to 2-Chloro Acids Esters

2-Chloro acid methyl esters were prepared in good yields treating 2-chloro aldehyde dimethyl acetals with trichloroisocyanuric acid in DMF.Aldehyde dimethyl acetals with the 2-halogen on a tertiary carbon atom were poorly reactive and could be oxidized efficiently only after their transformation into 1,3-dioxolanes.

Reductive coupling of methyl αbromo-α-chlorocarboxylates

CuBr-LiOCH3 in methanol efficiently promotes the reductive coupling of methyl α-bromo-α-chlorocarboxylates to dimethyl α,α′-dichloro-succinates.

Chlorination of Esters. I. Chlorination of Methyl Esters of Propanoic, Butanoic, Pentanoic and Hexanoic Acids. The Isomer Distribution of Monochloro Esters Formed

The chlorination of methyl ester with chlorine in the liquid and vapor phase and with sulfuryl chloride in the liquid phase has been investigated.The chlorination yields all possible monochloro esters isomers with the 2-chloro isomer in the smallest amount.The products were identified by NMR and mass spectrometry.The isomer distribution and mass spectra of products were studied in detail.