18546-09-3

Basic information

• Product Name: 3-O-Methyl-6-deoxy-L-glucose
• Synonyms: 3-O-Methyl-6-deoxy-L-glucose;6-Deoxy-3-O-methyl-L-glucose;Ceberose;L-Thevetose
• CAS NO: 18546-09-3
• Molecular Formula: C₇H₁₄O₅
• Molecular Weight: 178.18
• Mol File: 18546-09-3.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-O-Methyl-6-deoxy-L-glucose(CAS DataBase Reference)
• NIST Chemistry Reference: 3-O-Methyl-6-deoxy-L-glucose(18546-09-3)
• EPA Substance Registry System: 3-O-Methyl-6-deoxy-L-glucose(18546-09-3)

Safety Data

• Hazardous Substances Data: 18546-09-3(Hazardous Substances Data)

Upstream product

• 7647-01-0 hydrogenchloride 
• 64-19-7 acetic acid 
• 110098-43-6 14-hydroxy-3β-(O³-methyl-6-deoxy-α-L-glucopyranosyloxy)-19-oxo-5α,14β-bufa-20,22-dienolide 
• 5158-60-1 methyl-(O³-methyl-6-deoxy-α-D-altropyranoside) 

Downstream Products

• 112047-81-1 O³-methyl-D-arabino-6-deoxy-[2]hexosulose-bis-phenylhydrazone 
• 112047-81-1 O³-methyl-D-ribo-6-deoxy-[2]hexosulose-bis-phenylhydrazone 
• 112047-81-1 O³-methyl-L-arabino-6-deoxy-[2]hexosulose-bis-phenylhydrazone 

Relevant articles and documents

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New calogenin pregnane glycoside derivative from Huernia saudi- arabica and its Lipase and α-Glucosidase Inhibitory Activities

As ongoing investigation of Huernia saudi-arabica D.V.Field (Asclepiadaceae), a new steroidal pregnane glycoside (Huernioside A) was isolated from dichloromethane fraction (DCM); it was identified as 3β, 11, 14β, 20(R)-tetrahydroxy-pregna-5,9(11)-diene-3-O-β-D-thevetopyranosyl-(1-4)-β-D-cymaropyranoside(HCP) through analysis of 1D, 2D NMR besides ESI-MS data. The alcoholic extract of the aerial part (ALE), DCM and HCP showed inhibitory potential against pancreatic lipase compared to orilstat. Among the tested samples, the ALE and HCP exhibited a promising pancreatic lipase inhibitory commotion through IC50 values of 0.61 ± 0.15, 1.23 ± 0.07 mg/ml (equivalent to 88.8 μM), respectively. HCP was prevailed to have a mixed mode of inhibition as exposed by enzyme kinetic studies. Hydrophobic interactions were the major forces involved in ligand enzyme interactions. In contrast, moderate α-glucosidase inhibitory activities were evidenced for ALE and HCP (% inhibition: 24.8 ± 1.8 and 26.6 ± 2.5, respectively) compared to acarbose. This investigation is the first to report on the possible in vitro anti-obesity and anti-diabetic impact of H. saudi-arabica.

Two new 14, 15-secopregnane-type steroidal glycosides from the roots of Cynanchum limprichtii

Two new steroidal glycosides 1 and 2, along with three known ones (3–5), were isolated from the 95% ethanol extract of the roots of Cynanchum limprichtii Schltr. The structure of the new compounds was elucidated as 3-O-α-L-diginopyranosyl-(1→4)-β-D-digito