185994-78-9

Upstream product

• 96-32-2 bromoacetic acid methyl ester 
• 185995-59-9 1-(3-hydroxyphenyl)-2-(3,4-diphenylphenyl)ethane 
• 1700-31-8 3-benzyloxybenzyl bromide 
• 1700-30-7 (3-(benzyloxy)phenyl)methanol 
• 128133-59-5 1-ethynyl-3-(phenylmethoxy)benzene 
• 1356497-05-6 (3,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)trimethylsilane 
• 1356496-93-9 (3,4-diphenylphenyl)trimethylsilane 
• 1356496-95-1 (3-benzyloxy-3',4'-diphenyl)diphenylacetylene 
• 1356496-92-8 2,4-bis(trimethylsilyl)phenyl triflate 
• 17878-30-7 (2,4-dichlorophenoxy)trimethylsilane 
• 17864-01-6 2,4-bis(trimethylsilyl)phenyl trimethylsilyl ether 
• 76129-21-0 4-iodo-1,2-diphenylbenzene 
• 120-83-2 2,4-dichlorophenol 
• 61283-03-2 (1,1':2',1''-terphenyl)-4'-carbaldehyde 

Relevant academic research and scientific papers

Copper-catalyzed borylation reactions of alkynes and arynes

One, two, three, four: A copper(I)-phosphine complex catalyzes the diborylation of alkynes and arynes, and the tri- or tetraborylation of propargyl ethers (see scheme; pin=pinacolato). In the latter cases, the C-O bond(s) as well as the C≡C bond are borylated in one pot. Furthermore, a diborylation product serves as an intermediate in the efficient synthesis of ortho-terphenyls with pharmacological activity.

Antithrombotic effects of the novel inhibitor of thrombin-induced platelet aggregation and thrombus formation, 3-[2-([1,1':2',1'']-terphenyl-4'-yl)ethyl]phenoxyacetic acid

The new compound 3-[2-([1,1':2',1'']-terphenyl-4'-yl)ethyl]phenoxyacetic acid (F1070) was synthesized and its effects on platelet aggregation induced by thrombin, thrombin receptor agonist peptide (TRAP), ADP and collagen were evaluated in humans, guinea