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186086-71-5

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186086-71-5 Usage

Description

3-Pyrrolidin-1-yl-benzoic acid methyl ester is a versatile chemical compound belonging to the class of pyrrolidine derivatives. It is recognized for its potential anticonvulsant and anti-inflammatory properties, as well as its ability to act as a chelating agent in the manufacturing of various coordination compounds. 3-PYRROLIDIN-1-YL-BENZOIC ACID METHYL ESTER also serves as a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals, and has been explored for its potential as a building block in organic synthesis, showcasing its diverse applications across different fields.

Uses

Used in Pharmaceutical Industry:
3-Pyrrolidin-1-yl-benzoic acid methyl ester is used as an intermediate in the synthesis of various pharmaceuticals for its potential anticonvulsant and anti-inflammatory properties. It contributes to the development of new drugs that can address a range of health conditions by modulating the body's response to inflammation and seizures.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Pyrrolidin-1-yl-benzoic acid methyl ester is utilized as an intermediate in the production of agrochemicals, potentially enhancing crop protection and yield through its incorporation into various formulations designed to combat pests and diseases.
Used in Chemical Research:
3-Pyrrolidin-1-yl-benzoic acid methyl ester is employed as a chelating agent in the manufacturing of coordination compounds, which are essential in various chemical research applications, including catalysis and the development of new materials with unique properties.
Used in Organic Synthesis:
3-PYRROLIDIN-1-YL-BENZOIC ACID METHYL ESTER is also used as a building block in organic synthesis, providing a foundation for the creation of complex organic molecules with potential applications in various industries, such as pharmaceuticals, materials science, and specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 186086-71-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,0,8 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 186086-71:
(8*1)+(7*8)+(6*6)+(5*0)+(4*8)+(3*6)+(2*7)+(1*1)=165
165 % 10 = 5
So 186086-71-5 is a valid CAS Registry Number.

186086-71-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 3-pyrrolidin-1-ylbenzoate

1.2 Other means of identification

Product number -
Other names 3-pyrrolidin-1-yl-benzoic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:186086-71-5 SDS

186086-71-5Relevant articles and documents

Discovery of novel pyrrole-based scaffold as potent and orally bioavailable free fatty acid receptor 1 agonists for the treatment of type 2 diabetes

Li, Zheng,Pan, Miaobo,Su, Xin,Dai, Yuxuan,Fu, Mian,Cai, Xingguang,Shi, Wei,Huang, Wenlong,Qian, Hai

supporting information, p. 1981 - 1987 (2016/04/20)

The free fatty acid receptor 1 (FFA1) has gained significant interest as a novel antidiabetic target. Most of FFA1 agonists reported in the literature bearing a common biphenyl scaffold, which was crucial for toxicity verified by the researchers of Daiichi Sankyo. Herein, we describe the systematic exploration of non-biphenyl scaffold and further chemical modification of the optimal pyrrole scaffold. All of these efforts led to the identification of compound 11 as a potent and orally bioavailable FFA1 agonist without the risk of hypoglycemia. Further molecular modeling studies promoted the understanding of ligand-binding pocket and might help to design more promising FFA1 agonists.

Triaminophosphine ligands for carbon-nitrogen and carbon-carbon bond formation

-

Page/Page column 25-26; 34-35, (2008/12/05)

Methods and compounds are provided for the formation of carbon-nitrogen or carbon-carbon bonds comprising reacting an amine or an aryl boronic acid with an aryl halide in the presence of a palladium catalyst, a base, and a compound of formula II:

Cysteine protease inhibitors

-

, (2008/06/13)

of the formula (IV): where: R1=R′C(O), R′SO2, R′=a bicyclic, saturated or unsaturated, 8-12 membered ring system containing 0-4 hetero atoms selected from S, O and N, which is optionally substituted with up to four substituents independently selected from groups a), b) and c) below; or R′=a monocyclic, saturated or unsaturated, 5-7 membered ring containing 0-3 hetero atoms selected from S, O and N, which monocyclic ring bears at least one substituent selected from group a) and/or c) and which may optionally bear one or two further substituents selected from group b); R4=H, C1-7-alkyl, Ar-C1-7-alkyl, Ar, C3-7-cycloalkyl; C2-7alkenyl; R3=C1-7-alkyl, C2-C7 alkenyl, C2-C7 alkenyl, C3-7-cycloalkyl, Ar-C1-7-alkyl, Ar; R5=C1-7-alkyl, halogen, Ar-C1-7-alkyl, C1-3-alkyl-CONR3R4 or a bulky amine R6 is H, C1-7-alkyl, Ar-C1-7-alkyl, C1-3-alkyl-SO2-Rix, C1-3-alkyl-C(O)—NHRix or CH2XAr q is 0 or 1 have utility as inhibitors of cysteine proteases such as cathepsin K and falcipain.

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